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623-05-2

中文名稱 對(duì)羥基苯甲醇
英文名稱 4-Hydroxybenzyl alcohol
CAS 623-05-2
EINECS 編號(hào) 210-768-0
分子式 C7H8O2
MDL 編號(hào) MFCD00004658
分子量 124.14
MOL 文件 623-05-2.mol
更新日期 2024/12/20 09:11:13
623-05-2 結(jié)構(gòu)式 623-05-2 結(jié)構(gòu)式

基本信息

中文別名
對(duì)羥基苯甲醇
4-羥基苯甲醇
對(duì)羥基芐醇
4-羥基芐醇,98+%
4-羥基芐醇
英文別名
4-hydroxybenzenemethanol
4-HYDROXYBENZYL ALCOHOL
4-METHYLOLPHENOL
FEMA 3987
HYDROXYBENZYL-4 ALCOHOL
P-HYDROXYBENZYL ALCOHOL
P-(HYDROXYMETHYL)PHENOL
RARECHEM AL BD 0098
4-(Hydroxymethyl)phenol
alpha-Hydroxy-p-cresol
Benzyl alcohol, p-hydroxy-
Gastrodigenin
p-Methylolphenol
p-Hydroxy Benzyl Alcohol 4-Hydroxy Benzyl Alcohol
4-HYDROXYBENZYL ALCOHOL 98+%
4-HydroxybenzylAlcohol99%
p-Hydroxybenzyl
Benzenemethanol, 4-hydroxy-
PARA-HYDROXYBENZOYLALCOHOL
PARA-ALCOHOLPHENOL
所屬類別
化學(xué)試劑:芳香醇

物理化學(xué)性質(zhì)

外觀性狀可溶于甲醇、乙醇、DMSO等有機(jī)溶劑,來(lái)源于合歡皮。
熔點(diǎn)114-122 °C(lit.)
沸點(diǎn)251-253°C
密度1.1006 (rough estimate)
FEMA3987
折射率1.5035 (estimate)
閃點(diǎn)251-253°C
儲(chǔ)存條件2-8°C
溶解度水中的溶解度為6.7克/升
酸度系數(shù)(pKa)pK1:9.82 (25°C)
形態(tài)結(jié)晶粉末
顏色粉色至米色
氣味 (Odor)at 100.00 %. fruity bitter almond sweet coconut
香型fruity
水溶解性Soluble in water (6.7 mg/ml at 20°C), dioxane (100 mg/ml), 1N NaOH (50 mg/ml), DMSO, and methanol.
敏感性Light Sensitive/Air Sensitive
JECFA Number955
BRN1858967
InChIKeyBVJSUAQZOZWCKN-UHFFFAOYSA-N
LogP0.21
CAS 數(shù)據(jù)庫(kù)623-05-2(CAS DataBase Reference)
NIST化學(xué)物質(zhì)信息Benzenemethanol, 4-hydroxy-(623-05-2)
EPA化學(xué)物質(zhì)信息Benzenemethanol, 4-hydroxy-(623-05-2)

安全數(shù)據(jù)

危險(xiǎn)性符號(hào)(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險(xiǎn)性描述H319-H412
危險(xiǎn)品標(biāo)志Xi
危險(xiǎn)類別碼R36
安全說(shuō)明S26-S24/25
WGK Germany3
RTECS號(hào)DA4796800
Hazard NoteIrritant/Keep Cold/Air Sensitive/Light Sensitive
海關(guān)編碼29072900

應(yīng)用領(lǐng)域

用途一
用作有機(jī)合成中間體

化學(xué)品安全說(shuō)明書(shū)(MSDS)

常見(jiàn)問(wèn)題列表

用途
對(duì)羥基苯甲醇是加利車霉素綴合物中的合成試劑,用于治療急性髓細(xì)胞性白血病。 參與多酚氧化酶催化的酚氧化。 也用于制備抗瘧藥。
應(yīng)用
對(duì)羥基苯甲醇為醇類有機(jī)物,可用作有機(jī)合成中間體。
生物活性
4-Hydroxybenzyl alcohol是廣泛分布于各種植物中的酚類化合物。 具有抗炎,抗氧化,抗傷害感受活性。 神經(jīng)保護(hù)作用。 抑制腫瘤血管生成和生長(zhǎng)。
靶點(diǎn)

Human Endogenous Metabolite

體外研究

4-Hydroxybenzyl alcohol inhibits proliferation of eEND2 cells and suppresses the migration of eEND2 cells, accompanied by inhibition of actin filament reorganization.

4-Hydroxybenzyl alcohol induces apoptotic death of tumor cells.

體內(nèi)研究

4-Hydroxybenzyl alcohol possesses antiangiogenic, anti-inflammatory and anti-nociceptive activity possibly via its down-regulating activity on NO production.

4-Hydroxybenzyl alcohol (200 mg/kg) efficiently inhibits growth and angiogenesis of developing tumors.

4-Hydroxybenzyl alcohol ameliorates ischemic injury induced by transient focal cerebral ischemia in rats, and this neuroprotective effect may be partly related to attenuate apoptosis pathway.

對(duì)羥基苯甲醇價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱CAS號(hào)包裝價(jià)格
2024/11/08A131324-羥基芐醇, 99%
4-Hydroxybenzyl alcohol, 99%
623-05-250g923元
2024/11/08A131324-羥基芐醇, 99%
4-Hydroxybenzyl alcohol, 99%
623-05-2100g1665元
2024/11/08A131324-羥基芐醇, 99%
4-Hydroxybenzyl alcohol, 99%
623-05-2250g3559元
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