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ChemicalBook CAS DataBase List Sodium gluconate
527-07-1

Sodium gluconate synthesis

5synthesis methods
The calcium gluconate is added into the reaction kettle. Add sulfuric acid aqueous solution while stirring. After mixing for one hour, let it stand for a while and then get it filtered. The filter residue is CaSO4 and gets it removed. The filtrate is added into the neutralization kettle, and a proper amount of Na2CO3 aqueous solution is added to neutralize it. Finally get sodium gluconate through concentration, filtration and drying.
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Yield:527-07-1 90.9%

Reaction Conditions:

with oxygen;sodium carbonate in water at 20; for 1 h;Reagent/catalyst;Time;

Steps:

2.4 Catalytic Oxidation of Glucose into Sodium Gluconate

In a typical run, glucose (1.5 mmol, 270 mg) and Au/HAP (40 mg) was added to 10 mL of water with a magnetic stirring. Then, Na2CO3 (0.75 mmol, 80 mg) was added to the mixture and the reaction was started at room temperature by bubbling molecular oxygen (30 mL/min). After a certain reaction time, the Au/HAP catalyst was removed by centrifugation. Then the liquid solution was acidified with 0.05 M/L HCl until its pH <6. Finally, the liquid solutionwas analyzed by HPLC.

References:

Liu, Xianxiang;Yang, Yongjun;Su, Shengpei;Yin, Dulin [Catalysis Letters,2017,vol. 147,# 2,p. 383 - 390]

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