2-(Ethylamino)ethanol synthesis

10synthesis methods

Product Name:2-(Ethylamino)ethanol
CAS Number:110-73-6
Molecular formula:C4H11NO
Molecular Weight:89.14

75-21-8
231 suppliers
$33.29/crm44609

75-04-7
392 suppliers
$10.00/20mg

110-73-6
277 suppliers
$5.00/5g

Yield:110-73-6 94%

Reaction Conditions:

in water at 35; for 0.0444444 h;Temperature;

Steps:

1.b; 2.b; 3.b; 4.b; 5.b Synthesis of N-ethylethanolamine
Using Corning's high-throughput continuous flow microchannel reactor, prepare a 30% ethylene oxide aqueous solution and 70% ethylamine aqueous solution with a mass percentage concentration ofSet the flow rate of the ethylene oxide aqueous solution metering pump to 42.0mL/min,The flow rate of the ethylamine aqueous solution metering pump is 20.0mL/min, and the ethylene oxide aqueous solutionThe ethylamine aqueous solution was separately pumped into Corning's high-throughput continuous flow microchannel reactor to be preheated in the first independent module-the direct current preheating module at a temperature of 35°C;Then enter the second module-enhanced mass transfer mixing module through the A or B inlet of the Corning high-throughput continuous flow microchannel reactor respectively. The mixed reaction is carried out for 160s at a reaction temperature of 35°C, and the mixed liquid after the reaction From the outlet of Corning's high-throughput continuous flow microchannel reactor, collect the effluent of the microchannel reactor;After the effluent is dehydrated, N-ethylethanolamine is obtained with a yield of 94% and a liquid phase purity of 99.2%.

References:

Chengdu Aibike Pharmaceutical Technology Co., Ltd.;Wang Xinlong;Bai Linkui;Li Wei CN111995534, 2020, A Location in patent:Paragraph 0029; 0035-0037; 0043-0045; 0051-0053; 0059-0061

FullText

1120-64-5 Synthesis