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ChemicalBook CAS DataBase List 5-Chloro-2-pentanone
5891-21-4

5-Chloro-2-pentanone synthesis

13synthesis methods
-

Yield:5891-21-4 94.3%

Reaction Conditions:

with iron(III) chloride in diethyl ether; under 375.038 Torr; for 2.75 h;Reflux;Microwave irradiation;Pressure;Time;

Steps:

4.3

(3) mixing the prepared 2-methyl-4,5-dihydrofuran with diethyl ether into the reaction kettle,The control temperature is 80 ° C, FeCl3 is added, the stirring is uniform, and the control pressure is 0.05Mpa.After microwave treatment for 45 min, the reaction was stirred and refluxed for 2 h.After the reaction is over, add water and mix well.Stirring reaction for 2h, restore the room pressure at room temperature, collect the organic layer,Vacuum distillation,5-Chloro-2-pentanone was obtained.

References:

CN108586214,2018,A Location in patent:Paragraph 0023; 0032; 0041; 0046; 0050; 0054; 0059

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