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ChemicalBook CAS DataBase List 2-METHYL-2-OXAZOLINE
1120-64-5

2-METHYL-2-OXAZOLINE synthesis

12synthesis methods
-

Yield:1120-64-5 73%

Steps:

1 EXAMPLE 1

EXAMPLE 1 Preparation of 2-methyl-1,3-oxazoline was as follows. To 10 milliliters (ml) of tetramethylene sulfone (Sulfolane) was added N-(2-chloroethyl) acetamide (2 grams (g), 16 millimoles (mmole)) and 4 equivalents (10 g) of 40% potassium fluoride on alumina. This mixture was mechanically stirred for about two hours. The product was then distilled at 90° C under a vacuum of 550 mm Hg to give 1.018 g (a yield of about 73 percent).

References:

US5382665,1995,A

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