SRPK inhibitor
|
- $32 - $2691.1
- Product name: SRPK inhibitor
- CAS: 218156-96-8
- MF: C18H18F3N3O
- MW: 349.35
- EINECS:
- MDL Number:MFCD00116244
- Synonyms:4-Pyridinecarboxamide, N-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-;N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide SRPIN 340;SRPK inhibitor N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide;SRPIN 340;SRPIN340;SRPIN-340;SRPK inhibitor;N-(2-(piperidin-1-yl)-5-(trifluoroMethyl)phenyl)isonicotinaMide
31 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 10mg
- 10
- 5mg
- 50
- 25mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 1g
- ManufacturerAK Scientific
- Product numberSYN5233
- Product descriptionSRPIN340
- Packaging10mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY1863
- Product descriptionSRPIN340
- Packaging250mg
- Price$737
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5233
- Product descriptionSRPIN340
- Packaging100mg
- Price$1080
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2032
- Product descriptionSRPIN340
- Packaging25mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB2032
- Product descriptionSRPIN340
- Packaging50mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2200
- Product descriptionSRPIN340 99%
- Packaging10mg
- Price$104.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545917
- Product descriptionSRPIN340 >98%
- Packaging5mg
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545917
- Product descriptionSRPIN340 >98%
- Packaging25mg
- Price$508.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181148
- Product descriptionSRPIN340 >98%
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181148
- Product descriptionSRPIN340 >98%
- Packaging250mg
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb181148
- Product descriptionSRPIN340 >98%
- Packaging1000mg
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16284
- Product descriptionSRPIN340 ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16284
- Product descriptionSRPIN340 ≥95%
- Packaging5mg
- Price$86
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16284
- Product descriptionSRPIN340 ≥95%
- Packaging10mg
- Price$153
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16284
- Product descriptionSRPIN340 ≥95%
- Packaging25mg
- Price$335
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1681
- Product descriptionSRPIN340 99.99%
- Packaging5mg
- Price$72
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5233 | SRPIN340 | 10mg | $210 | 2021-12-16 | Buy |
| AK Scientific | Y1863 | SRPIN340 | 250mg | $737 | 2021-12-16 | Buy |
| AK Scientific | SYN5233 | SRPIN340 | 100mg | $1080 | 2021-12-16 | Buy |
| ApexBio Technology | B2032 | SRPIN340 | 25mg | $240 | 2021-12-16 | Buy |
| ApexBio Technology | B2032 | SRPIN340 | 50mg | $360 | 2021-12-16 | Buy |
| Axon Medchem | Axon2200 | SRPIN340 99% | 10mg | $104.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545917 | SRPIN340 >98% | 5mg | $187 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545917 | SRPIN340 >98% | 25mg | $508.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181148 | SRPIN340 >98% | 100mg | $690.2 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181148 | SRPIN340 >98% | 250mg | $1356.6 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb181148 | SRPIN340 >98% | 1000mg | $2691.1 | 2021-12-16 | Buy |
| Cayman Chemical | 16284 | SRPIN340 ≥95% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 16284 | SRPIN340 ≥95% | 5mg | $86 | 2024-03-01 | Buy |
| Cayman Chemical | 16284 | SRPIN340 ≥95% | 10mg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 16284 | SRPIN340 ≥95% | 25mg | $335 | 2024-03-01 | Buy |
| ChemScene | CS-1681 | SRPIN340 99.99% | 5mg | $72 | 2021-12-16 | Buy |
Properties
Boiling point :395.9±42.0 °C(Predicted)
Density :1.306±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :11.09±0.70(Predicted)
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Density :1.306±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :11.09±0.70(Predicted)
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Serine/arginine-rich protein kinase 1 (SRPK1) targets proteins that contain multiple serine/arginine (SR) dipeptides, including SR-rich splicing factor 1, SRSF1. SRPIN340 is an isonicotinamide compound that inhibits SRPK1 (Ki = 0.89 μM). It is about 10-fold less effective against SRPK2 and does not inhibit the related SRPKs, Clk1 and Clk4. SRPIN340 suppresses the propagation of Sindbis virus in Vero cells and the replication of hepatitis C virus in Huh7/Rep-Feo-2a cells. By blocking SRPK1-mediated phosphorylation of SRSF1, SRPIN340 modulates alternative splicing of VEGF, reducing neovascularization both in cells and in animals.More related product prices
SR-18292 PF-03814735 2-METHOXYESTRADIOL Saracatinib Axitinib N-((4,5-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-9-(3-fluorophenyl)-2-morpholino-9H-purin-6-amine SR17018 SR27897 SR 0987 N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide SR 1078 SR-9243 SR8278 SR9009 Z-VAD-FMK Olaparib 2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamideRelated product price
- SR-18292
$32-2100 - PF-03814735
$37-1126 - 2-METHOXYESTRADIOL
$31-510
