99% purity available from supplier Axon Medchem, prime source of life science reagents for your research" />

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SRPIN 340

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2200

CAS [218156-96-8]

MF C18H18F3N3O
MW 349.35

  • Purity: 99%
  • Soluble in DMSO

SRPIN 340

Description

Selective ATP-competitive inhibitor of SRPK kinase activity (Ki 0.89 μM for SRPK1; 99.2% inhibition of RS-repeat peptide substrate phosphorylation at 10μM). SRPIN340 does not inhibit other classes of Serine-Arginine-Rich Protein Kinases (SRPKs) significantly, including Clk1 and Clk4 and >140 other SR kinases. SRPIN 340 promotes SRp75 degradation, and dose dependently suppressed HCV 1b and 2a replication (EC50 values of 4.7 μM and 15.8 μM resp.) and propagation of Sindbis and HCV-JFH1 viruses in cell culture.
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Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €335.00 In Stock
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Size Unit Price Stock
2 x 10 mg €140.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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