IMR-1
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- $55 - $1600
- Product name: IMR-1
- CAS: 310456-65-6
- MF: C15H15NO5S2
- MW: 353.41
- EINECS:-0
- MDL Number:MFCD04141288
- Synonyms:IMR-1;[2-Methoxy-4-[(4-oxo-2-thioxo-5-thiazolidinylidene)methyl]phenoxy]acetic acid ethyl ester;IMR-1, >98%;Acetic acid, 2-[2-methoxy-4-[(4-oxo-2-thioxo-5-thiazolidinylidene)methyl]phenoxy]-, ethyl ester;IMR-1 >=98% (HPLC);2-Methoxy-4-(4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-phenoxy]-acetic acid ethyl ester;IMR 1,IMR1,IMR-1,Notch,Inhibitor,inhibit;2-Methoxy-4-(4-oxo-2-thioxo-thiazolidin-5-ylidenemethyl)-phenoxy]-acetic acid ethyl este，IMR-1
17 prices
Selected condition：
Brand
- Ambeed
- ApexBio Technology
- Cayman Chemical
- ChemScene
- DC Chemicals
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAmbeed
- Product numberA802072
- Product descriptionIMR-1 97%
- Packaging5mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA802072
- Product descriptionIMR-1 97%
- Packaging10mg
- Price$162
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA802072
- Product descriptionIMR-1 97%
- Packaging25mg
- Price$274
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA802072
- Product descriptionIMR-1 97%
- Packaging50mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6110
- Product descriptionIMR-1
- Packaging5mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6110
- Product descriptionIMR-1
- Packaging25mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6110
- Product descriptionIMR-1
- Packaging100mg
- Price$630
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27920
- Product descriptionIMR-1
- Packaging5mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27920
- Product descriptionIMR-1
- Packaging10mg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27920
- Product descriptionIMR-1
- Packaging25mg
- Price$268
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5753
- Product descriptionIMR-1 98.59%
- Packaging5mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5753
- Product descriptionIMR-1 98.59%
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5753
- Product descriptionIMR-1 98.59%
- Packaging50mg
- Price$380
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5753
- Product descriptionIMR-1 98.59%
- Packaging100mg
- Price$630
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9756
- Product descriptionIMR-1 >98%
- Packaging100mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9756
- Product descriptionIMR-1 >98%
- Packaging250mg
- Price$800
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Ambeed | A802072 | IMR-1 97% | 5mg | $96 | 2021-12-16 | Buy |
| Ambeed | A802072 | IMR-1 97% | 10mg | $162 | 2021-12-16 | Buy |
| Ambeed | A802072 | IMR-1 97% | 25mg | $274 | 2021-12-16 | Buy |
| Ambeed | A802072 | IMR-1 97% | 50mg | $357 | 2021-12-16 | Buy |
| ApexBio Technology | B6110 | IMR-1 | 5mg | $80 | 2021-12-16 | Buy |
| ApexBio Technology | B6110 | IMR-1 | 25mg | $280 | 2021-12-16 | Buy |
| ApexBio Technology | B6110 | IMR-1 | 100mg | $630 | 2021-12-16 | Buy |
| Cayman Chemical | 27920 | IMR-1 | 5mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 27920 | IMR-1 | 10mg | $121 | 2024-03-01 | Buy |
| Cayman Chemical | 27920 | IMR-1 | 25mg | $268 | 2024-03-01 | Buy |
| ChemScene | CS-5753 | IMR-1 98.59% | 5mg | $55 | 2021-12-16 | Buy |
| ChemScene | CS-5753 | IMR-1 98.59% | 10mg | $95 | 2021-12-16 | Buy |
| ChemScene | CS-5753 | IMR-1 98.59% | 50mg | $380 | 2021-12-16 | Buy |
| ChemScene | CS-5753 | IMR-1 98.59% | 100mg | $630 | 2021-12-16 | Buy |
| DC Chemicals | DC9756 | IMR-1 >98% | 100mg | $450 | 2021-12-16 | Buy |
| DC Chemicals | DC9756 | IMR-1 >98% | 250mg | $800 | 2021-12-16 | Buy |
Properties
storage temp. :2-8°C(protect from light)
solubility :Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 9 mg/ml with warming).
form :solid
color :Yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
solubility :Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 9 mg/ml with warming).
form :solid
color :Yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Safety Information
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Description
Inhibitor of Mastermind Recruitment-1 (IMR-1, 310456-65-6) disrupts the recruitment of Mastermind-like 1 to the Notch transcriptional activation complex (NTC) on chromatin, which attenuates Notch target gene transcription.1?IC50=26 μM (in vitro assay). IMR-1 inhibits the growth of Notch-dependent cell lines and attenuates the growth of patient-derived tumor xenografts. The ethyl ester is hydrolyzed by intracellular esterases which produces the free acid compound (IMR-1A), IC50=0.5 μM (in vitro?assay). Binding of IMR-1 to NTC is non-covalent and reversible.1Related product price
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$5-2400 - GDC-0879
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