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Doxapram hydrochloride monohydrate

Doxapram hydrochloride monohydrate Struktur
7081-53-0
CAS-Nr.
7081-53-0
Englisch Name:
Doxapram hydrochloride monohydrate
Synonyma:
stimulexin;DOXAPRAM HCL;DoxapraM HCL API;Doxapram Hydrochoride;DOXAPRAM HYDROCHLORIDE;Doxapram hydrochloride CRS;DoxapraM Hydrochloride, USP;doxapramhydrochloridehydrate;Dopram hydrochloride hydrate;Doxapram hydrochloride monohyd
CBNumber:
CB6189200
Summenformel:
C24H30N2O2.ClH.H2O
Molgewicht:
432.99
MOL-Datei:
7081-53-0.mol

Doxapram hydrochloride monohydrate Eigenschaften

Schmelzpunkt:
217-219°
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
Soluble in water, in alcohol and in methylene chloride.
Aggregatzustand
Solid
Farbe
White to off-white
InChIKey
ZOMBFZRWMLIDPX-UHFFFAOYSA-N
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
RIDADR  UN 2811 6.1 / PGIII
HS Code  2934990002
Toxizit?t LD50 orally in rats: 261 mg/kg (Goldenthal)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizit?t oral Kategorie 3 Achtung GHS hazard pictogramssrc="/GHS06.jpg" width="20" height="20" /> P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit

Doxapram hydrochloride monohydrate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Doxapram is a central respiratory stimulant. It increases respiration and phrenic nerve activity in anesthetized cats at a dose of 1.0 mg/kg. Doxapram acts through carotid chemoreceptors, lacking activity in anesthetized cats following carotid denervation. Formulations containing doxapram have been used to increase respiration in patients with chronic pulmonary disease, respiratory depression induced by drug overdose, and to stimulate deep breathing post-anesthesia.

Chemische Eigenschaften

White or almost white, crystalline powder.

Verwenden

antibacterial

Definition

ChEBI: The monohydrate form of doxapram hydrochloride. A central and respiratory stimulant with a brief duration of action, it is used as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, nd of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.

Allgemeine Beschreibung

Doxapram, 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone hydrochloride hydrate (Dopram), has an obscuremolecular mechanism of action. Overall, it stimulatesrespiration by action on peripheral carotid chemoreceptors.It has use as a respiratory stimulant postanesthetically, afterCNS depressant drug overdose, in chronic obstructive pulmonarydiseases, and in the apneas. Dopram is administeredexclusively by intravenous injection. Because of the benzylalcohol content of the injectable formulation, Dopram mustnever be given to neonates.

Doxapram hydrochloride monohydrate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Doxapram hydrochloride monohydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 201)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Anhui Ruihan Technology Co., Ltd
+8617756083858
daisy@anhuiruihan.com China 973 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497
sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Hangzhou FandaChem Co.,Ltd.
+8615858145714
FandaChem@Gmail.com China 9087 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32957 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Shanghai Worldyang Chemical Co.,Ltd.
+86-021-56795779 +8613651600618
sales@worldyachem.com China 1243 58
Shanghai Longyu Biotechnology Co., Ltd.
+8619521488211
info@longyupharma.com China 2541 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873
sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58

7081-53-0()Verwandte Suche:


  • 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinonehydrochloridehydr
  • 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinonmonohydrochloride
  • doxapramhydrochloridehydrate
  • stimulexin
  • 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-dephenyl-2-pyrrolidinone hydrochloride monohydrate
  • DOXAPRAM HCL
  • DOXAPRAM HYDROCHLORIDE
  • doxapram hydrochloride monohydrate
  • 1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenyl-pyrrolidin-2-one hydrate hydrochloride
  • 1-ethyl-4-(2-morpholin-4-ylethyl)-3,3-diphenylpyrrolidin-2-one hydrate hydrochloride
  • 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidone hydrate hydrochloride
  • Doxapram Hydrochloride (200 mg)
  • Doxapram Hydrochoride
  • 2-Pyrrolidinone, 1-ethyl-4-2-(4-morpholinyl)ethyl-3,3-diphenyl-, monohydrochloride, monohydrate
  • DOTHIEPINHYDROCHLORIDE,ANHYDROUS
  • 2-Pyrrolidinone, 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-, hydrochloride, hydrate (1:1:1)
  • 1-Ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone monohydrochloride monohydrate
  • Doxapram Hydrochloride Doxapram Hydrochloride
  • 1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-Pyrrolidinone, monohydrochloride, monohydrate(8CI)
  • 1-Ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone, hydrochloride, hydrate(1:1:1)
  • DoxapraM Hydrochloride, USP
  • (4S)-1-ethyl-4-[2-(Morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one
  • DoxapraM HCL API
  • 1-Ethyl-4-(2-Morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone hydrochloridehydrate
  • 1-Ethyl-4-[2-(4-Morpholinyl)ethyl]-3,3-diphenyl-2-Pyrrolidinone, Monohydrochloride, Monohydrate (9CI)
  • DoxapraM Hydrochoride Monohydrate
  • Doxapram hydrochloride monohyd
  • 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone hydrate hydrochloride
  • Dopram hydrochloride hydrate
  • DOPRAM HYDROCHLORIDE HYDRATE;STIMULEX HYDROCHLORIDE HYDRATE;RESPIRAM HYDROCHLORIDE HYDRATE
  • Respiram hydrochloride hydrate
  • Stimulex hydrochloride hydrate
  • Doxapram hydrochloride CRS
  • (4RS)-1-Ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3- diphenylpyrrolidin-2-one hydrochloride
  • oxapramhydrochloridemonohydrate
  • Doxapram hydrochloride monohydrate USP/EP/BP
  • 1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenylpyrrolidin-2-one hydrochloride hydrate
  • Doxapram hydrochloride (AHR-619)
  • Doxapram Hydrochloride (1225000)
  • 7081-53-0
  • C24H30N2O2HCl
  • C24H33ClN2O3
  • C24H30N2O2HClH2O
  • Inhibitors
  • API
  • MECLAN
  • Other APIs
  • Pharmaceutical material and intermeidates
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