| Identification | More | [Name]
3-NITROPYRIDINE | [CAS]
2530-26-9 | [Synonyms]
3-NITROPYRIDINE
Pyridine, 3-nitro-
5-Nitropyridine | [Molecular Formula]
C5H4N2O2 | [MDL Number]
MFCD00234974 | [Molecular Weight]
124.1 | [MOL File]
2530-26-9.mol |
| Chemical Properties | Back Directory | [Appearance]
white to yellow needle-like crystals | [Melting point ]
35-40 °C | [Boiling point ]
216°C | [density ]
1,33 g/cm3 | [refractive index ]
1.4800 (estimate) | [Fp ]
216°C | [storage temp. ]
Flammables area | [form ]
Liquid | [pka]
pK1:0.79(+1) (25°C,μ=0.02) | [color ]
Clear colorless | [BRN ]
111969 | [CAS DataBase Reference]
2530-26-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn-F | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R11:Highly Flammable. | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
2811 | [WGK Germany ]
3 | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29333999 |
| Hazard Information | Back Directory | [Chemical Properties]
white to yellow needle-like crystals | [Uses]
3-NITROPYRIDINE is used in the novel synthesis of biologically active nitro heterocyclic compounds.
| [Synthesis]
In 1993 Suzuki and co-workers reported the nitration of pyridine with nitrogen dioxide and ozone in dichloromethane at room temperature. They obtained a 3.5 % yield of 3-nitropyridine and 1.2 % of 3,5-dinitropyridine.
3-Nitropyridines can also be synthesized by oxidation of 3-aminopyridine with hydrogen peroxide in fuming sulphuric acid in 45% yield. Nitration of 2,6-dichloropyridine with nitronium tetrafluoroborate gave a 11% yield of 3-nitropyridine after dehalogenation. 3-nitropyridine has also been prepared from 2- chloro-3-nitropyridine. |
|
| Company Name: |
Alfa Aesar
|
| Tel: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|