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ChemicalBook CAS DataBase List QUINAZOLIN-4-YLAMINE
15018-66-3

QUINAZOLIN-4-YLAMINE synthesis

14synthesis methods
-

Yield: 77%

Reaction Conditions:

with formamide at 200; for 0.166667 h;Microwave irradiation;Sealed vial;

Steps:

4.3. General procedures for the syntheses of quinazolin4-amines
General procedure: Method B: Formimidamide or acetimidamide intermediates were suspended in formamide (40 equiv) and InCl3 (1 equiv), or not, in a sealed vial and were irradiated at 400 W under microwaves. The residue was cooled to room temperature, filtrated, washed with water and dried.

References:

Loidreau, Yvonnick;Besson, Thierry [Tetrahedron,2011,vol. 67,# 26,p. 4852 - 4857] Location in patent:experimental part

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