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ChemicalBook CAS DataBase List Triethyl orthoformate
122-51-0

Triethyl orthoformate synthesis

10synthesis methods
-

Yield:122-51-0 92%

Reaction Conditions:

with boron trifluoride in Hexadecane at 110; for 18 h;Autoclave;

Steps:

3 Example 1. Preparation of triethyl orthobenzoate

General procedure: In a 50ml stainless steel autoclave with a magnetic stir bar, add 1.50g (10mmol) ethyl benzoate,In 0.1g n-hexadecane (internal standard) and 7.40g (100mmol) ether solution containing 0.068g (1mmol) boron trifluoride, heat up to 110 and react for 6.0 hours. After the reaction is over, cool down to 0-5 .The sample was analyzed by gas phase, and the conversion rate of ethyl benzoate was 98%, and the yield of triethyl orthobenzoate was 95%.

References:

CN111470954,2020,A Location in patent:Paragraph 0021; 0022

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