Fesoterodine Related Impurity 4 synthesis
- Product Name:Fesoterodine Related Impurity 4
- CAS Number:214601-12-4
- Molecular formula:C22H29NO2
- Molecular Weight:339.47
214601-54-4
1 suppliers
inquiry
214601-12-4
18 suppliers
inquiry
Yield:-
Reaction Conditions:
with hydrogen;5%-palladium/activated carbon in methanol at 25 - 30; under 2206.72 - 2942.29 Torr; for 8 h;autoclave;
Steps:
33
Example-33: Preparation of (R)-N,N-diisopropyl-3-(5-formyl-2-hydroxyphenyl)-3- phenyl propanamine compound of formula-ll(R)-4-(benzyloxy)-3 -(3 -(diisopropylamino)- 1 -phenylpropyl) benzaldehyde (20 gm), methanol (200 ml) and 5% Pd/C (10 gm) were charged into an autoclave at 25- 30°C under nitrogen atmosphere. 3-4 Kg/Cm2 hydrogen gas pressure was applied to the reaction mixture for 8 hrs at 25-30°C. After the completion of the reaction, filtered the reaction mixture through hyflow bed and washed with methanol. Distilled off the solvent completely form the filtrate under reduced pressure to get the title compound. Yield: 14 gm;
References:
WO2012/98560,2012,A2 Location in patent:Page/Page column 66
106-41-2
496 suppliers
$13.00/5g
214601-12-4
18 suppliers
inquiry
621-82-9
354 suppliers
$29.12/100G
214601-12-4
18 suppliers
inquiry
156755-23-6
55 suppliers
$52.00/100mg
214601-12-4
18 suppliers
inquiry