(L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCYLAGMATINE HEMIHYDRATE
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- $28 - $2025
- Product name: (L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCYLAGMATINE HEMIHYDRATE
- CAS: 66701-25-5
- MF: C15H27N5O5
- MW: 357.41
- EINECS:613-978-4
- MDL Number:MFCD07366493
- Synonyms:(2S,3S)-3-(((S)-1-((4-Guanidinobutyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylic acid;(2S,3S)-3-(((S)-1-((4-Guanidinobutyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carb;oxiranecarboxylicacid,3-(((1-(((4-((aminoiminomethyl)amino)butyl)amino)carbon ;proteinaseinhibitore64 ;thiolproteaseinhibitor ;TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-*(4-GU ANIDINO)BUT;(2S, 3S)-TRANS-EPOXY SUCCINYL-L-LEUCYLAMIDO-(4-GUANIDINO) BUTANE;L-TRANS-3-CARBOXYOXIRAN-2-CARBONYL-L-LEUCYLAGMATINE
44 prices
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Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- ApexBio Technology
- Apolloscientific
- Cayman Chemical
- Chem-Impex
- ChemScene
- CSNpharm
- DC Chemicals
- Iris Biotech GmbH
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 10
- 100mg
- 250mg
- 500mg
- 50
- 10mM(in 1mL DMSO)
- 1unit
- 5mg
- 10mg
- 25mg
- 50mg
- 1g
- ManufacturerAK Scientific
- Product number7701AE
- Product description(2S,3S)-3-(((S)-1-((4-Guanidinobutyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylicacid
- Packaging50mg
- Price$425
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ62933
- Product descriptionE-64
- Packaging5mg
- Price$109.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ62933
- Product descriptionE-64
- Packaging25mg
- Price$455.65
- Updated2024-03-01
- Buy
- ManufacturerAmbeed
- Product numberA252147
- Product descriptionE-64 99+%
- Packaging5mg
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA252147
- Product descriptionE-64 99+%
- Packaging10mg
- Price$117
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA252147
- Product descriptionE-64 99+%
- Packaging25mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA252147
- Product descriptionE-64 99+%
- Packaging50mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA252147
- Product descriptionE-64 99+%
- Packaging1g
- Price$1582
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2576
- Product descriptionE-64
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2576
- Product descriptionE-64
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2576
- Product descriptionE-64
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2576
- Product descriptionE-64
- Packaging25mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2576
- Product descriptionE-64
- Packaging100mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2576
- Product descriptionE-64
- Packaging250mg
- Price$980
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIMI2157
- Product descriptionE-64 95%
- Packaging5mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIMI2157
- Product descriptionE-64 95%
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 7701AE | (2S,3S)-3-(((S)-1-((4-Guanidinobutyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylicacid | 50mg | $425 | 2021-12-16 | Buy |
| Alfa Aesar | J62933 | E-64 | 5mg | $109.65 | 2024-03-01 | Buy |
| Alfa Aesar | J62933 | E-64 | 25mg | $455.65 | 2024-03-01 | Buy |
| Ambeed | A252147 | E-64 99+% | 5mg | $69 | 2021-12-16 | Buy |
| Ambeed | A252147 | E-64 99+% | 10mg | $117 | 2021-12-16 | Buy |
| Ambeed | A252147 | E-64 99+% | 25mg | $198 | 2021-12-16 | Buy |
| Ambeed | A252147 | E-64 99+% | 50mg | $357 | 2021-12-16 | Buy |
| Ambeed | A252147 | E-64 99+% | 1g | $1582 | 2021-12-16 | Buy |
| ApexBio Technology | A2576 | E-64 | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A2576 | E-64 | 5mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A2576 | E-64 | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
| ApexBio Technology | A2576 | E-64 | 25mg | $140 | 2021-12-16 | Buy |
| ApexBio Technology | A2576 | E-64 | 100mg | $420 | 2021-12-16 | Buy |
| ApexBio Technology | A2576 | E-64 | 250mg | $980 | 2021-12-16 | Buy |
| Apolloscientific | BIMI2157 | E-64 95% | 5mg | $51 | 2021-12-16 | Buy |
| Apolloscientific | BIMI2157 | E-64 95% | 10mg | $90 | 2021-12-16 | Buy |
Properties
Melting point :>170°C (dec.)
Density :1.44±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :H2O: 20 mg/mL, clear, colorless
pka :3.16±0.40(Predicted)
form :White solid
color :White or off-white
Water Solubility :Soluble in DMSO (25mg/ml), or water (20mg/ml)
Sensitive :Light Sensitive
BRN :1405664
Stability :Stable for 1 year from date of purchase as supplied.
InChIKey :LTLYEAJONXGNFG-DCAQKATOSA-N
SMILES :O1[C@H](C(N[C@H](C(NCCCCNC(N)=N)=O)CC(C)C)=O)[C@H]1C(O)=O
CAS DataBase Reference :66701-25-5(CAS DataBase Reference)
Density :1.44±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :H2O: 20 mg/mL, clear, colorless
pka :3.16±0.40(Predicted)
form :White solid
color :White or off-white
Water Solubility :Soluble in DMSO (25mg/ml), or water (20mg/ml)
Sensitive :Light Sensitive
BRN :1405664
Stability :Stable for 1 year from date of purchase as supplied.
InChIKey :LTLYEAJONXGNFG-DCAQKATOSA-N
SMILES :O1[C@H](C(N[C@H](C(NCCCCNC(N)=N)=O)CC(C)C)=O)[C@H]1C(O)=O
CAS DataBase Reference :66701-25-5(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
It is used as a broad spectrum cysteine proteinase and calpain activation inhibitor. Additionally, Prevotella intermediate studies report that E-64 blocks the breakdown of methaemoglobin and the oxidation of oxyhaemoglobin by InpA. E-64 has also been used to study excystation in Giardia lamblia. E-64 is an inhibitor of Calpain, cathepsin K and cathepsin S. E-64 is an effective ligand for affinity purification of cysteine proteases. When coupled to a thiolated affinity matrix, binding is no longer irreversible, but specificity is retainedRelated product price
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