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ChemicalBook >> CAS DataBase List >> Levobupivacaine hydrochloride

Levobupivacaine hydrochloride

Levobupivacaine hydrochloride price.
  • $60 - $1504.5
  • Product name: Levobupivacaine hydrochloride
  • CAS: 27262-48-2
  • MF: C18H29ClN2O
  • MW: 324.89
  • EINECS:1308068-626-2
  • MDL Number:MFCD01704265
  • Synonyms:TIMTEC-BB SBB001337;(S)-(-)-BUPIVACAINE HCL;(S)-(-)-BUPIVACAINE HYDROCHLORIDE;(S)-(-)-1-N-BUTYL-2',6'-DIMETHYL-2-PIPERIDINCARBOXANILID HYDROCHLORIDE;(S)-(-)-1-BUTYL-2-(2,6-XYLYLCARBAMOYL)-PIPERIDINE HYDROCHLORIDE;s-(-)-1-butyl-2',6'-pipecoloxylidide hydrochloride;(s)-1-butyl-2’,6’-piperidinecarboxamidemonohydrochloride ;(s)-1-butyl-n-(2,6-dimethylphenyl)-2-piperidinecarboxamidemonohydrochloride
33 prices
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  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 10mg
  • 50MG
  • 100mg
  • 200mg
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  • 2g
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  • ManufacturerAK Scientific
  • Product numberN768
  • Product descriptionLevobupivacaineHCl
  • Packaging1g
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH37643
  • Product descriptionLevobupivacaine hydrochloride 98%
  • Packaging250mg
  • Price$148.05
  • Updated2023-01-06
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH37643
  • Product descriptionLevobupivacaine hydrochloride 98%
  • Packaging1g
  • Price$438.9
  • Updated2023-01-06
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003158
  • Product descriptionLEVOBUPIVACAINE HYDROCHLORIDE 95.00%
  • Packaging50MG
  • Price$224.7
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003158
  • Product descriptionLEVOBUPIVACAINE HYDROCHLORIDE 95.00%
  • Packaging1G
  • Price$1443.75
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number2871
  • Product descriptionLevobupivacaine Hydrochloride
  • Packaging100mg
  • Price$65
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number2871
  • Product descriptionLevobupivacaine Hydrochloride
  • Packaging1g
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2871
  • Product descriptionLevobupivacaine Hydrochloride
  • Packaging10g
  • Price$475
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb146292
  • Product descriptionLevobupivacaine HCL >99%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb134764
  • Product descriptionBupivacaine HCL >99%
  • Packaging1g
  • Price$765
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb146292
  • Product descriptionLevobupivacaine HCL >99%
  • Packaging250mg
  • Price$912.9
  • Updated2021-12-16
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  • ManufacturerBiorbyt Ltd
  • Product numberorb146292
  • Product descriptionLevobupivacaine HCL >99%
  • Packaging1g
  • Price$1504.5
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFB149833
  • Product descriptionLevobupivacaine hydrochloride
  • Packaging500mg
  • Price$65
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFB149833
  • Product descriptionLevobupivacaine hydrochloride
  • Packaging1g
  • Price$90
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFB149833
  • Product descriptionLevobupivacaine hydrochloride
  • Packaging2g
  • Price$150
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFB149833
  • Product descriptionLevobupivacaine hydrochloride
  • Packaging5G
  • Price$300
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific N768 LevobupivacaineHCl 1g $95 2021-12-16 Buy
Alfa Aesar H37643 Levobupivacaine hydrochloride 98% 250mg $148.05 2023-01-06 Buy
Alfa Aesar H37643 Levobupivacaine hydrochloride 98% 1g $438.9 2023-01-06 Buy
American Custom Chemicals Corporation API0003158 LEVOBUPIVACAINE HYDROCHLORIDE 95.00% 50MG $224.7 2021-12-16 Buy
American Custom Chemicals Corporation API0003158 LEVOBUPIVACAINE HYDROCHLORIDE 95.00% 1G $1443.75 2021-12-16 Buy
AvaChem 2871 Levobupivacaine Hydrochloride 100mg $65 2021-12-16 Buy
AvaChem 2871 Levobupivacaine Hydrochloride 1g $95 2021-12-16 Buy
AvaChem 2871 Levobupivacaine Hydrochloride 10g $475 2021-12-16 Buy
Biorbyt Ltd orb146292 Levobupivacaine HCL >99% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb134764 Bupivacaine HCL >99% 1g $765 2021-12-16 Buy
Biorbyt Ltd orb146292 Levobupivacaine HCL >99% 250mg $912.9 2021-12-16 Buy
Biorbyt Ltd orb146292 Levobupivacaine HCL >99% 1g $1504.5 2021-12-16 Buy
Biosynth Carbosynth FB149833 Levobupivacaine hydrochloride 500mg $65 2021-12-16 Buy
Biosynth Carbosynth FB149833 Levobupivacaine hydrochloride 1g $90 2021-12-16 Buy
Biosynth Carbosynth FB149833 Levobupivacaine hydrochloride 2g $150 2021-12-16 Buy
Biosynth Carbosynth FB149833 Levobupivacaine hydrochloride 5G $300 2021-12-16 Buy

Properties

Melting point :254 °C (dec.)(lit.)
alpha :-12.5 º (c=2, water)
storage temp. :2-8°C
solubility :H2O: soluble20mg/mL, clear
form :powder
color :white to beige
optical activity :[α]/D -10 to -14°, c = 1.0 in H2O
InChI :InChI=1/C18H28N2O.ClH/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3;/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21);1H/t16-;/s3
InChIKey :SIEYLFHKZGLBNX-NTISSMGPSA-N
SMILES :C([C@@H]1CCCCN1CCCC)(=O)NC1C(=CC=CC=1C)C.Cl |&1:1,r|
CAS DataBase Reference :27262-48-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Levobupivacaine was first launched in the US for the production of local anesthesia for surgery and obstetrics and for post-operative pain management. It is the (S)-enantiomer of the long acting, highly potent local anesthetic bupivacaine (Marcaine) that can be prepared by a three step sequence from (S)-pipecolic acid or from (S)-lysine by oxidative deamination and stereospecific ring closure to (S)-pipecolamide core structure. Levobupivacaine exhibits its long-acting local anesthetic effect by blocking neuronal sodium channel ion flow in nerve axons. Clinical studies demonstrated an efficacy and a general profile closely resembling those of the racemic bupivacaine currently in use; however, it produced an enhanced safety profile, in particular substantially reduced (about one-third) cardiotoxicity (less effect on myocardial contractility and QT, prolongation) and CNS depressive side effects. Onset and duration of blockade were also equivalent or even better.

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