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ChemicalBook >> CAS DataBase List >> TAE226 (NVP-TAE226)

TAE226 (NVP-TAE226)

TAE226 (NVP-TAE226) price.
  • $34 - $4725
  • Product name: TAE226 (NVP-TAE226)
  • CAS: 761437-28-9
  • MF: C23H25ClN6O3
  • MW: 468.94
  • EINECS:
  • MDL Number:MFCD12031516
  • Synonyms:NVP-TAE 226;TAE226;TAE226 (NVP-TAE226);2-((5-Chloro-2-((2-methoxy-4-morpholinophenyl)-amino)pyrimidin-4-yl)amino)-N-methylbenzamide;Benzamide, 2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-;NVP-TAE 226 2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methylbenzamide;2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methylbenzamide;TAE226 (NVP-TAE226) USP/EP/BP
31 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number1836AC
  • Product description2-((5-Chloro-2-((2-methoxy-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide
  • Packaging1mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1836AC
  • Product description2-((5-Chloro-2-((2-methoxy-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide
  • Packaging10mg
  • Price$338
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121000
  • Product descriptionNVP-TAE226 98+%
  • Packaging1mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121000
  • Product descriptionNVP-TAE226 98+%
  • Packaging5mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121000
  • Product descriptionNVP-TAE226 98+%
  • Packaging10mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121000
  • Product descriptionNVP-TAE226 98+%
  • Packaging25mg
  • Price$114
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121000
  • Product descriptionNVP-TAE226 98+%
  • Packaging50mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121000
  • Product descriptionNVP-TAE226 98+%
  • Packaging100mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121000
  • Product descriptionNVP-TAE226 98+%
  • Packaging250mg
  • Price$383
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121000
  • Product descriptionNVP-TAE226 98+%
  • Packaging1g
  • Price$954
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8557
  • Product descriptionTAE226(NVP-TAE226)
  • Packaging5mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8557
  • Product descriptionTAE226(NVP-TAE226)
  • Packaging10mM(in 1mL DMSO)
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8557
  • Product descriptionTAE226(NVP-TAE226)
  • Packaging10mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8557
  • Product descriptionTAE226(NVP-TAE226)
  • Packaging100mg
  • Price$1180
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60371
  • Product descriptionTAE226(NVP-TAE226) ≥98%
  • Packaging5mg
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT153807
  • Product descriptionNVP TAE 226
  • Packaging10mg
  • Price$185
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1836AC 2-((5-Chloro-2-((2-methoxy-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide 1mg $124 2021-12-16 Buy
AK Scientific 1836AC 2-((5-Chloro-2-((2-methoxy-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide 10mg $338 2021-12-16 Buy
Ambeed A121000 NVP-TAE226 98+% 1mg $34 2021-12-16 Buy
Ambeed A121000 NVP-TAE226 98+% 5mg $68 2021-12-16 Buy
Ambeed A121000 NVP-TAE226 98+% 10mg $88 2021-12-16 Buy
Ambeed A121000 NVP-TAE226 98+% 25mg $114 2021-12-16 Buy
Ambeed A121000 NVP-TAE226 98+% 50mg $148 2021-12-16 Buy
Ambeed A121000 NVP-TAE226 98+% 100mg $192 2021-12-16 Buy
Ambeed A121000 NVP-TAE226 98+% 250mg $383 2021-12-16 Buy
Ambeed A121000 NVP-TAE226 98+% 1g $954 2021-12-16 Buy
ApexBio Technology A8557 TAE226(NVP-TAE226) 5mg $119 2021-12-16 Buy
ApexBio Technology A8557 TAE226(NVP-TAE226) 10mM(in 1mL DMSO) $130 2021-12-16 Buy
ApexBio Technology A8557 TAE226(NVP-TAE226) 10mg $189 2021-12-16 Buy
ApexBio Technology A8557 TAE226(NVP-TAE226) 100mg $1180 2021-12-16 Buy
Arctom CFN60371 TAE226(NVP-TAE226) ≥98% 5mg $238 2021-12-16 Buy
Biosynth Carbosynth FT153807 NVP TAE 226 10mg $185 2021-12-16 Buy

Properties

Density :1.349
storage temp. :Store at -20°C
solubility :≥23.45 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :14.57±0.46(Predicted)
color :White to khaki

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NVP-TAE226 is an inhibitor of focal adhesion kinase (FAK; IC50 = 5.5 nM) and the related proline-rich tyrosine kinase 2-β (PYK2β; IC50 = 5 nM). It can also inhibit the insulin-like growth factor 1 receptor (IC50 = 0.16 μM) as well as the activity of its downstream target genes such as MAPK and Akt. NVP-TAE226 has been shown to inhibit glioma and ovarian tumor growth in in vivo tumor models.