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ChemicalBook >> CAS DataBase List >> N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide

N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide

N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide price.
  • $30 - $1700
  • Product name: N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide
  • CAS: 362003-83-6
  • MF: C25H25N3O2S
  • MW: 431.55
  • EINECS:
  • MDL Number:MFCD01988824
  • Synonyms:adamantane-1-carboxylic acid (2-benzoylamino-benzothiazol-6-yl)amide;N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide;NVP 231;NVP-231;NVP231;CS-1722;NVP-231;NVP 231;NVP231;Tricyclo[3.3.1.13,7]decane-1-carboxamide, N-[2-(benzoylamino)-6-benzothiazolyl]-;NVP231,inhibit,mcf-7,cancer,cerk,Apoptosis,NVP 231,Inhibitor,NCI-H358,NVP-231
30 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1MG
  • 5mg
  • 10mg
  • 50
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3941AH
  • Product descriptionN-[2-(Benzoylamino)-6-benzothiazolyl]-tricyclo[3.3.1.1(3,7)]decane-1-carboxamide
  • Packaging25mg
  • Price$329
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA149574
  • Product descriptionNVP-231 98+%
  • Packaging5mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA149574
  • Product descriptionNVP-231 98+%
  • Packaging10mg
  • Price$41
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA149574
  • Product descriptionNVP-231 98+%
  • Packaging50mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA149574
  • Product descriptionNVP-231 98+%
  • Packaging100mg
  • Price$223
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA149574
  • Product descriptionNVP-231 98+%
  • Packaging250mg
  • Price$556
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA149574
  • Product descriptionNVP-231 98+%
  • Packaging1g
  • Price$1418
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000845
  • Product descriptionNVP-231 95.00%
  • Packaging1MG
  • Price$135.45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000845
  • Product descriptionNVP-231 95.00%
  • Packaging5MG
  • Price$701.95
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000845
  • Product descriptionNVP-231 95.00%
  • Packaging25MG
  • Price$1042.97
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1235
  • Product descriptionNVP231
  • Packaging10mg
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1235
  • Product descriptionNVP231
  • Packaging25mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1235
  • Product descriptionNVP231
  • Packaging50mg
  • Price$169
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1235
  • Product descriptionNVP231
  • Packaging100mg
  • Price$304
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1600
  • Product descriptionNVP231 99%
  • Packaging25mg
  • Price$313.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13858
  • Product descriptionNVP-231 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3941AH N-[2-(Benzoylamino)-6-benzothiazolyl]-tricyclo[3.3.1.1(3,7)]decane-1-carboxamide 25mg $329 2021-12-16 Buy
Ambeed A149574 NVP-231 98+% 5mg $30 2021-12-16 Buy
Ambeed A149574 NVP-231 98+% 10mg $41 2021-12-16 Buy
Ambeed A149574 NVP-231 98+% 50mg $112 2021-12-16 Buy
Ambeed A149574 NVP-231 98+% 100mg $223 2021-12-16 Buy
Ambeed A149574 NVP-231 98+% 250mg $556 2021-12-16 Buy
Ambeed A149574 NVP-231 98+% 1g $1418 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000845 NVP-231 95.00% 1MG $135.45 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000845 NVP-231 95.00% 5MG $701.95 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000845 NVP-231 95.00% 25MG $1042.97 2021-12-16 Buy
ApexBio Technology B1235 NVP231 10mg $43 2021-12-16 Buy
ApexBio Technology B1235 NVP231 25mg $90 2021-12-16 Buy
ApexBio Technology B1235 NVP231 50mg $169 2021-12-16 Buy
ApexBio Technology B1235 NVP231 100mg $304 2021-12-16 Buy
Axon Medchem Axon1600 NVP231 99% 25mg $313.5 2021-12-16 Buy
Cayman Chemical 13858 NVP-231 ≥98% 1mg $32 2024-03-01 Buy

Properties

Melting point :246-248 °C(Solv: isopropanol (67-63-0); water (7732-18-5))
Density :1.398±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :DMSO: >10mg/mL
pka :9.09±0.70(Predicted)
form :powder
color :white to off-white
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :MVSSJPGNLQPWSW-UHFFFAOYSA-N
SMILES :C12(C(NC3C=C4SC(NC(=O)C5=CC=CC=C5)=NC4=CC=3)=O)CC3CC(CC(C3)C1)C2

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Ceramides have diverse roles in cell differentiation, proliferation, and apoptosis. Ceramide kinase converts ceramide to ceramide-1-phosphate (C1P), removing the effects of ceramide in favor of those directed by C1P. NVP-231 is a potent, reversible inhibitor of ceramide kinase (IC50 = 12 nM). It has minimal effect on several other lipid kinases, including sphingosine kinases 1 and 2. In cells in which exogenous short chain ceramide is converted to C1P, resulting in cell death, NVP-231 prevents both C1P synthesis and cell death. In mouse dermal microvascular endothelial cells, where ceramide kinase increases capillary-like tube formation, NVP-231 (100 nM) inhibits C1P formation as well as tube formation.

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