精油中的“戰(zhàn)痘之神”非茶樹莫屬了，早上冒起一顆又大又紅的痘痘，用棉簽蘸取茶樹精油點涂上去，晚上到家就消了大半。這神奇的功效，你知道背后的原理嗎？

茶樹精油中富含4-萜烯醇，也多虧了這個小小的分子，才讓我們擺脫了痘痘煩惱。接下來一起揭開它的神秘面紗吧！

功效應(yīng)用

抗炎

4-萜烯醇可以抑制TNF、IL-1、IL-8、前列腺素E2的過度表達^[1]，減少炎癥反應(yīng)，起到抗炎效果；

抗細菌

4-萜烯醇對莫匹羅星、夫西地酸、萬古霉素、甲氧西林和利奈唑胺耐藥的菌株具有活性，對大量金黃色葡萄球菌分離株具有良好的抗葡萄球菌活性^[2]；

抗真菌

4-萜烯醇對于白色念珠菌等引起生殖系統(tǒng)問題的真菌有良好抑菌效果，并且可以增強氟康唑?qū)Π咨钪榫目咕芰?sup>[3,4]；

抗腫瘤

4-萜烯醇對Hep-G2(人肝癌細胞）有劑量依賴性殺傷作用^[5]，通過誘導(dǎo)Hep-G2細胞凋亡、DNA斷裂、細胞遷移抑制和亞G1期阻滯而發(fā)揮抗癌作用。

應(yīng)用領(lǐng)域

4-萜烯醇用于日化調(diào)香可廣泛用于配置香辛類香精，此外也可應(yīng)用于臨床上藥品、科學(xué)研究，目前抗菌和改善慢病方面有較好的實驗效果。

參考文獻

[1]Pazyar N, Yaghoobi R, Bagherani N, Kazerouni A. A review of applications of tea tree oil in dermatology. Int J Dermatol. 2013;52(7):784-790.

[2]Ferrini AM, Mannoni V, Aureli P, et al. Melaleuca alternifolia essential oil possesses potent anti-staphylococcal activity extended to strains resistant to antibiotics. Int J Immunopathol Pharmacol. 2006;19(3):539-544.

[3]Mondello F, De Bernardis F, Girolamo A, Cassone A, Salvatore G. In vivo activity of terpinen-4-ol, the main bioactive component of Melaleuca alternifolia Cheel (tea tree) oil against azole-susceptible and -resistant human pathogenic Candida species. BMC Infect Dis. 2006;6:158.

[4]Mertas A, Garbusińska A, Szliszka E, Jureczko A, Kowalska M, Król W. The influence of tea tree oil (Melaleuca alternifolia) on fluconazole activity against fluconazole-resistant Candida albicans strains. Biomed Res Int. 2015;2015:590470.

[5]Liu S, Zhao Y, Cui HF, Cao CY, Zhang YB. 4-Terpineol exhibits potent in vitro and in vivo anticancer effects in Hep-G2 hepatocellular carcinoma cells by suppressing cell migration and inducing apoptosis and sub-G1 cell cycle arrest. J BUON. 2016;21(5):1195‐1202.