Calciumdi(acetat) Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
WEISSE BIS BRAUNEODER GRAUE KRISTALLE MIT CHARAKTERISTISCHEM GERUCH.
CHEMISCHE GEFAHREN
Zersetzung beim Erhitzen über 160°C unter Bildung von Acetond?mpfen und Calciumcarbonat. Reagiert sehr heftig mit starken S?uren unter Bildung vonEssigs?urerauchen.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den K?rper durch Inhalation und durch Verschlucken.
INHALATIONSGEFAHREN
Eine bel?stigende Partikelkonzentration in der Luft kann beim Dispergieren schnell erreicht werden.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: Die Substanz reizt die Augen, die Haut und die Atemwege.
LECKAGE
Verschüttetes Material in Beh?ltern sammeln. Reste mit viel Wasser wegspülen. Pers?nliche Schutzausrüstung: Atemschutzger?t, P1-Filter für inerte Partikel.
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Calcium acetate is a chemical compound which is calcium salt of acetic acid. It has the formula Ca(C
2H
3O
2)
2. Its standard name is calcium acetate, while calcium ethanoate is the systematic name. An older name is acetate of lime. The anhydrous form is very hygroscopic; therefore the monohydrate (Ca(CH
3COO)
2?H
2O) is the common form.
Chemische Eigenschaften
Calcium acetate occurs as a white or almost white, odorless or
almost odorless, hygroscopic powder.
Verwenden
Calcium Acetate is the calcium salt of acetic acid which functions
as a sequestrant and mold control agent. it contains approximately
25% calcium. it is a white odorless powder which is readily soluble
in water with a solubility of approximately 37 g in 100 g water at
0°c. its solubility decreases with increasing temperature, with a sol-
ubility of approximately 29 g in 100 g of water at 100°c.
Vorbereitung Methode
Calcium acetate can be prepared by soaking calcium carbonate (found in eggshells, or in common carbonate rocks such as lime stone or marble) in vinegar:
CaCO
3 + 2CH
3COOH → Ca(CH
3COO)
2 + H2O + CO
2 Since both reagents would have been available pre-historically, the chemical would have been observable as crystals then.
synthetische
Produced by calcium hydroxide neutralization of acetic acid.
Definition
ChEBI: The calcium salt of acetic acid. It is used, commonly as a hydrate, to treat hyperphosphataemia (excess phosphate in the blood) in patients with kidney disease: the calcium ion combines with dietary phosphate to form (insoluble) calcium phosphate, which is
excreted in the faeces.
Allgemeine Beschreibung
Calcium Acetate belongs to the group of calcium salts, widely used as phosphorus binders in patients with chronic renal failure.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmazeutische Anwendungen
Calcium acetate is used as a preservative in oral and topical
formulations.
Therapeutically, parenteral calcium acetate acts as a source of
calcium ions for hypocalcemia or electrolyte balance. Oral
calcium acetate is used as a complexing agent for hyperphosphatemia
in dialysis patients. Calcium acetate is also used in the
food industry as a stabilizer, buffer and sequestrant.
Sicherheitsprofil
Poison by intravenous
and intraperitoneal routes. Mutation data
reported. See also CALCIUM
COMPOUNDS. When heated to
decomposition it emits acrid smoke and
fumes.
Sicherheit(Safety)
Calcium acetate is used in oral and topical formulations. The pure
form of calcium acetate is toxic by IP and IV routes.
LD
50 (mouse, IP): 0.075 g/kg
LD
50 (mouse, IV): 0.052 g/kg
LD
50 (rat, oral): 4.28 g/kg
Lager
Calcium acetate is stable although very hygroscopic, and so the
monohydrate is the common form. It decomposes on heating (above
1608℃) to form calcium carbonate and acetone.
Store in well-closed airtight containers.
l?uterung methode
Recrystallise it from water (3mL/g) by partial evaporation in a desiccator. [Beilstein 2 IV 113.]
Inkompatibilit?ten
Calcium acetate is incompatible with strong oxidizing agents and
moisture.
Regulatory Status
GRAS listed. Accepted for use as a food additive in Europe.
Included in the FDA Inactive Ingredients Database (oral suspensions
and tablets; topical emulsions, lotions, and creams). Included
in nonparenteral medicines (oral tablets) licensed in the UK.
Calciumdi(acetat) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
