Cyclophosphamide monohydrate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R45:Kann Krebs erzeugen.
R25:Giftig beim Verschlucken.
R61:Kann das Kind im Mutterleib sch?digen.
R46:Kann vererbbare Sch?den verursachen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Chemische Eigenschaften

White to Off-White Solid

Verwenden

Cyclophosphamide monohydrate is used to treat cancers, autoimmune disorders and AL amyloidosis. It is a nitrogen mustard alkylating agent and reacts with deoxyribonucleic acid (DNA) to get its alkylated derivative. It is also involved in cancer research as a tool that induces apoptosis in tumor cells.

Definition

ChEBI: The monohydrate of cyclophosphamide.

Allgemeine Beschreibung

Fine white crystalline powder with a slightly bitter taste. Little or no odor.

Air & Water Reaktionen

Water soluble. Sensitive to moisture and light. Aqueous solutions may be kept for a few hours above room temperature, but hydrolysis occurs at temperatures above 86°F. Cyclophosphamide monohydrate undergoes both specific acid and specific base catalysis at extreme pHs. Spontaneous hydrolysis in aqueous solutions.

Reaktivit?t anzeigen

Polymerization can occur at temperatures > 120° F. Cyclophosphamide monohydrate reacts with strong oxidizing agents, strong acids and strong bases. Benzyl alcohol increases rate of hydrolysis.

Brandgefahr

Cyclophosphamide monohydrate is probably combustible.

Sicherheitsprofil

Confirmed human carcinogen. Poison by ingestion and intravenous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl-, PO,, and NOx.

Cyclophosphamide monohydrate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Cyclophosphamide monohydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hebei Weibang Biotechnology Co., Ltd	+8617732866630	bess@weibangbio.com	China	18151	58
Hebei Jingbo New Material Technology Co., Ltd	+8619931165850	hbjbtech@163.com	China	1000	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20284	58
Hebei Saisier Technology Co., LTD	+86-18400010335 +86-18034520335	admin@hbsaisier.cn	China	1015	58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.	+86-18600796368 +86-18600796368	sales@sjar-tech.com	China	456	58
HebeiShuoshengImportandExportco.,Ltd	+86-18532138899 +86-18532138899	L18532138899@163.com	China	939	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	18751	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60

6055-19-2()Verwandte Suche:

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• 2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE
• 2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE HYDRATE
• 2-[BIS(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE 2-OXIDE MONOHYDRATE
• ENDOXON
• CYCLOPHOSPHAMIDE HYDRATE
• CYCLOPHOSPHAMIDE MONOHYDRATE
• CYCLOPHOSPHAMID MONOHYDRATE
• bis(2-chloroethyl)phosphoramide cyclic propanolamide ester monohydrate
• N,N-BIS(2-CHLOROETHYL)TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORIN-2-AMINE-2-OXIDE MONOHYDRATE
• n,n-bis(beta-chloroethyl)-n',o-propylenephosphoric acid ester amide monohydrate
• TIMTEC-BB SBB003026
• > 100 Kgyclophosphamide monohydrate
• Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester~Cyclophosphane
• cyclophosphamide isopac
• Cyclophos phamide USP
• CYCLOPHOSPHAMIDE MONOHYDRATE, 98+%
• CyclophosphamideSterile,Usp28
• Cyclophosphamidemonohaydrate
• CYCLOPHOSPHAMIDE 1-HYDRATE
• 2H-1,3,2-Oxazaphosphorin-2-amine, N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide, monohydrate
• CyclophosphaMide,awater
• 2-(Bis(2-chloroethyl)aMino)-1,3,2-oxazaphosphinane 2-oxide hydrate
• 2-oxide-N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine, hydrate (1:1)
• Bis(2-chloroethyl)phosphoramide cyclic propanolamide este
• Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester m
• (bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-oxide
• 1-bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridinemonohydrate
• 2-(bis(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphocyclohexane2-oxidemonohydr
• 2-(di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane-2-oxidemonohydra
• 2h-1,3,2-oxazaphosphorine,tetrahydro-2-(bis(2-chloroethyl)amino)-,2-oxide,mo
• -2monohydrate
• cyclicn’,o-propyleneesterofn,n-bis(2-chloroethyl)phosphorodiamidicacidm
• endoxanmonohydrate
• n,n-bis(2-chloroethyl)tetrahydro-2h-1,3,2-oxaphosphorin-2-amine,2-oxidemono
• N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphos-phorin-2-amine2-oxide
• n,n-bis(beta-chloroethyl)-n’,o-propylenephosphoricacidesteramidemonohydra
• n,n-bis(beta-chloroethyl)-n’,o-trimethylenephosphoricacidesterdiamidemono
• Procy-tox
• n,n-bis(beta-cloraethyl)n’-o-propylenphosphorildiamidmonohydratum
• N,N-Bis-2-chloroethyl-N’,O-propylenephosphoricesterdiamidemonohydrate
• n,n-di(2-chloroethyl)amino-n,o-propylenephosphoricacidesterdiamidemonohy
• CYCLOPHOPHAMIDEMONOHYDRATE
• CYCLOPHOSPHAMIDE,MONOHYDRATE,USP
• CYCLOPHOSPHAMIDE(HYDRATED)
• cyclophosphamide，CTX
• 2h-1,3,2-oxazaphosphorine, tetrahydro-2-(bis(2-chloroethyl)amino)-, 2-oxide, mo (bis(chloro-2-ethyl)amino)-2-tetrahydro-3,4,5,6-oxazaphosphorine-1,3,2-o xide 1-bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridine monohydrate 2-(bis(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphocyclohexane 2-oxide monohydr 2-(di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane-2-oxide monohydra cyclophosphamide hydrate cyclophosphamide monohydrate endoxan monohydrate
• Cycloblastin
• Cyclophosphamide monohydrate, 97+%
• Cytoxan, 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
• 2H-1,3,2-Oxazaphosphorine, tetrahydro-2-(bis(2-chloroethyl)amino)-, 2-oxide, monohydrate
• N,N-Bis(2-chloroethyl)-2-oxo-1-oxa-3-aza-2$l^{5}-phosphacyclohexan-2-amine hydrate
• CyclophosphamideUsp27
• Cyclophosphamide monohydrate,2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide, Cytoxan
• Cyclophosphamide (500 mg) (FOR U.S. SALE ONLY)
• Cyclophosphamide mon
• Cyclophosphamide (500 mg) (International Restricted Sales Item)
• (2S)-2-[bis(2-chloroethyl)aMino]-1,3,2$l^{5}-oxazaphosphinan-2-one
• CyclophosphaMide Monohydrate, 97% 1GR