5,6-Dichloronicotinic acid
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- CAS-Nr.
- 41667-95-2
- Englisch Name:
- 5,6-Dichloronicotinic acid
- Synonyma:
- 2,3-dichloropyridine-5-carboxylic acid;5,6-DichL;5,6-Dichloro;TIMTEC-BB SBB003623;Avatrhopal Impurity 45;5,6-DICHLORONICOTINIC A;Avatrombopag Impurity 10;Avatroposide impurities16;5,6-DICHLORONICOTINIC ACID;5,6-DichloronicotinicAcid>
- CBNumber:
- CB5261891
- Summenformel:
- C6H3Cl2NO2
- Molgewicht:
- 192
- MOL-Datei:
- 41667-95-2.mol
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5,6-Dichloronicotinic acid Eigenschaften
- Schmelzpunkt:
- 164-168 °C(lit.)
- Siedepunkt:
- 342.1±37.0 °C(Predicted)
- Dichte
- 1.612±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- pka
- 2.87±0.10(Predicted)
- Aggregatzustand
- Powder
- Farbe
- White to beige to tan
- BRN
- 383740
- InChI
- InChI=1S/C6H3Cl2NO2/c7-4-1-3(6(10)11)2-9-5(4)8/h1-2H,(H,10,11)
- InChIKey
- RNRLTTNKVLFZJS-UHFFFAOYSA-N
- SMILES
- C1=NC(Cl)=C(Cl)C=C1C(O)=O
- CAS Datenbank
- 41667-95-2(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi |
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| R-S?tze: |
36/37/38 |
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| S-S?tze: |
22-24/25-36-26 |
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| WGK Germany |
3 |
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| HazardClass |
IRRITANT |
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| HS Code |
29339900 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
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5,6-Dichloronicotinic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
white to off-white crystalline powder
Verwenden
5,6-Dichloronicotinic acid is a dihalonicotinic acid. It is used in the preparation of 5-chloro-6-iodonicotinic acid by iodine displacement.
Application
5,6-Dichloronicotinic acid is a compound that can be synthesized by reacting methyl ketones with chloroacetic acid. It is used in the synthesis of maleic anhydride and has been shown to inhibit the catalysis of acetylcholine chloride. It has also been shown to have an inhibitory effect on Alzheimer's disease. The kinetic mechanism for this inhibition occurs through the hydrolysis step of 5,6-Dichloronicotinic acid by magnesium chloride in hexane solution. The reactive acylation reaction proceeds when it reacts with acetic anhydride in the presence of pyridine.
5,6-Dichloronicotinic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5,6-Dichloronicotinic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 417)Lieferanten
41667-95-2()Verwandte Suche:
- 5,6-DICHLORO-3-PYRIDINECARBOXYLIC ACID
- 5,6-DICHLORONICOTINIC ACID
- 5,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID
- TIMTEC-BB SBB003623
- 5,6-Dichloropyridine-3-carboxylicacid,96%
- 5,6-Dichloro
- 5,6-DICHLORONICOTINIC ACID 98+%
- 5,6-Dichloronicotinic acid, 5,6-Dichloropyridine-3-carboxylic acid
- 5,6-Dichloropyridine-3-carboxylic acid, 98+%
- 5,6-Dichloropyridine-3-carboxylic acid, 5-Carboxy-2,3-dichloropyridine
- 5,6-Dichloronicotinic acid 97%
- 5,6-DichloronicotinicAcid>
- 5,6-DichL
- 3-Pyridinecarboxylic acid, 5,6-dichloro-
- Avatrombopag Impurity 10
- 5,6-Dichloronicotinic acid ISO 9001：2015 REACH
- 5,6-DICHLORONICOTINIC A
- 2,3-dichloropyridine-5-carboxylic acid
- Avatroposide impurities16
- (4-cyclohexylpiperazin-1-yl)(5,6-dichloropyridin-3-yl)methanone
- Avatrhopal Impurity 45
- 41667-95-2
- 1667-95-2
- Pyridines
- Heterocyclic Building Blocks
- Halogenated Heterocycles
- Building Blocks
- Chloropyridines
- Halopyridines
- Heterocycle-Pyridine series
- Chloropyridines
- Halopyridines
- Pyridine
- Building Blocks
- C5 to C6
- C6 to C7
- Chemical Synthesis
- Halogenated Heterocycles
- Heterocyclic Building Blocks
- Pyridines
- pharmacetical
- Organic acids
- Pyridines, Pyrimidines, Purines and Pteredines
- Intermediate
