Natriumdesoxycholat
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- CAS-Nr.
- 302-95-4
- Bezeichnung:
- Natriumdesoxycholat
- Englisch Name:
- Sodium deoxycholate
- Synonyma:
- SODIUM CHOLEATE;DEOXYCHOLIC ACID SODIUM SALT;SODIUM DESOXYCHOLATE;NSC 681065;sodium 3-B1;OXIDE EXTRACT;na-desoxycholat;Sodium deoxychoL;-dihydroxy-5-B2;deoxycholatesodium
- CBNumber:
- CB4452346
- Summenformel:
- C24H41NaO4
- Molgewicht:
- 416.58
- MOL-Datei:
- 302-95-4.mol
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Natriumdesoxycholat Eigenschaften
- Schmelzpunkt:
- 357-365 °C
- alpha
- 44 º (c=2, H2O)
- Dichte
- 1.012 at 20.07℃
- Dampfdruck
- 0Pa at 20℃
- Flammpunkt:
- >110°C (own results)
- storage temp.
- room temp
- L?slichkeit
- water: soluble1 gm in 10 ml, clear, colorless to very faintly yellow
- Aggregatzustand
- Powder
- Farbe
- Yellow-tan
- PH
- 7.5-9.0 (20g/l, H2O, 20℃)
- Geruch (Odor)
- Odorless
- S?ure-Base-Indikators(pH-Indikatoren)
- 7 - 10
- Optische Aktivit?t
- [α]20/D +44±2°, c = 2% in H2O
- Wasserl?slichkeit
- 330 g/L (15 ºC)
- BRN
- 3581950
- LogP
- 5.35 at 22℃ and pH5.7
- Oberfl?chenspannung
- 41.8mN/m at 1g/L and 20℃
- CAS Datenbank
- 302-95-4(CAS DataBase Reference)
- EPA chemische Informationen
- Cholan-24-oic acid, 3,12-dihydroxy-, monosodium salt, (3.alpha.,5.beta.,12.alpha.)- (302-95-4)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22-37 |
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| S-S?tze: |
22-24/25 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
FZ2250000 |
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| F |
3-10 |
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| TSCA |
Yes |
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| HS Code |
29181930 |
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| Toxizit?t |
LD50 orally in Rabbit: 1370 mg/kg |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Natriumdesoxycholat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R37:Reizt die Atmungsorgane.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
Chemische Eigenschaften
Sodium deoxycholate is white to cream crystalline powder
Verwenden
Sodium deoxycholate is used as a component in cell lysis buffers.
Allgemeine Beschreibung
Sodium deoxycholate is a bile salt and an ionic detergent. Bile salts work along with lipids/fats/cholesterol and form mixed micelles in the intestine. These micelles help in fat digestion and absorption through the intestinal wall.
Biologische Aktivit?t
Sodium deoxycholate (SDC) is an anionic detergent which has been used both to destroy infectious viruses and to fractionate viral components. Sodium deoxycholate begins to bind to the virus at less than 0.1 mM free equilibrium concentration. It causes lysis of the viral membrane at 0.9 +/- 0.1 mM free equilibrium concentration when 2.2 +/- 0.2 - 103 mol of sodium deoxycholate are bound per mol of the virus. The liberation of proteins from the membrane begins at 1.5 +/- 0.1 mM sodium deoxycholate, and the proteins released are virtually free from phospholipids above 2.0 mM sodium deoxycholate. The overall mechanism of sodium deoxycholate solubilization of the viral membrane resembles that of Triton X-100 and sodium dodecyl sulphate, except that with sodium deoxycholate, the various stages of membrane disruption occur at about 10-fold higher equilibrium free detergent concentrations. At sodium deoxycholate concentrations higher than 2.3 mM, the viral spike glycoproteins can be separated by sucrose gradient centrifugation or gel filtration into constituent polypeptides E1, E2 and E3[1-2].
Sicherheitsprofil
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NasO.
l?uterung methode
Recrystallise it from EtOH and dry it in an oven at 100o. The solution is freed from soluble components by repeated extraction with acid-washed charcoal. [Beilstein 10 IV 1608.]
Natriumdesoxycholat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Natriumdesoxycholat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 530)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
|
Wuhu Nuowei chemistry Co., Ltd.
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+86-0553-2911116-802 +undefined17756524438
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sales1@nuowei-chem.com |
China |
1638 |
58 |
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Shaanxi Pioneer Biotech Co., Ltd .
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+8613259417953
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sales@pioneerbiotech.com |
China |
1287 |
58 |
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Chengdu ChenLv Herb Co.,Ltd
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+86-13608205856; +undefined13608205856
|
maryextract@126.com |
China |
127 |
58 |
|
Hebei Fengmu Trading Co., Ltd.
|
+8613393234347
|
Lyla@fengmuchem.com |
China |
2946 |
58 |
|
Hebei Weibang Biotechnology Co., Ltd
|
+8615531157085
|
abby@weibangbio.com |
China |
8810 |
58 |
|
Wuhan Fortuna Chemical Co., Ltd
|
+86-027-59207850
|
info@fortunachem.com |
China |
5975 |
58 |
|
Hebei Chuanghai Biotechnology Co,.LTD
|
+86-13131129325
|
sales1@chuanghaibio.com |
China |
5889 |
58 |
|
Hong Kong Excellence Biotechnology Co., Ltd.
|
|
ada@sh-teruiop.com |
China |
875 |
58 |
|
Henan Fengda Chemical Co., Ltd
|
+86-371-86557731 +86-13613820652
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info@fdachem.com |
China |
20284 |
58 |
|
Shandong Juchuang Chemical Co., LTD
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+undefined15030412209
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admin@juchuangchem.com |
China |
387 |
58 |
302-95-4(Natriumdesoxycholat)Verwandte Suche:
- na-desoxycholat
- natrium-3-alpha,12-alpha-dihydroxycholanat
- sodium7-deoxycholate
- sodiumdeoxycholicacid
- 3α,12α-Dihydroxy-5β-cholanic acid sodium salt
- 17B-(1-METHYL-3-CARBOXYPROPYL)ETIOCHOLANE-3A,12A-DIOL SODIUM SALT
- SODIUM DEOXYCHOLATE
- CHOLEIC ACID SODIUM SALT
- DESOXYCHOLIC ACID SODIUM SALT
- DEOXYCHOLIC ACID NA-SALT
- sodium 3-alpha,12-alpha-dihydroxy-5-beta-cholan-24-oate
- Deoxidization sodium cholate
- SODIUM DEOXYCHOLATE (LOT US)
- Deoxycholic acid, sodium salt, extra pure, 99%
- SODIUMDISOXYCHOLATE
- DEOXYCHLOIC ACID SODIUM SALT, FOR ELECTROPHORESIS
- 3a,12a-Dihydroxy-5b-cholan-24-oic acid sodium salt
- SODIUM DESOXYCHOLAT
- 5-beta-Cholan-24-oic acid, 3-alpha,12-alpha-dihydroxy, sodium salt
- Cholan-24-oic acid, 3,12-dihydroxy-, monosodium salt, (3a,5b,12a)-
- Deoxycholic acid monosodium salt
- Sodium (4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
- sodium (4R)-4-((3R,5R,10S,12S,13R,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
- Sodium deoxycholate (synthetic)
- OXIDE EXTRACT
- Deoxycholic acid, sodium salt, 99%, extra pure
- Sodium Deoxycholate [for Electrophoresis]
- Deoxycholic acid sodium
- Sodium deoxycholate ,98%
- SodiuM 3,12-dihydroxycholanate
- sodium 3-α,12-α-dihydroxy-5-β-cholan-24-oate
- 3α,12.α-Dihydroxy-5β-cholan-24-oic Acid MonosodiuM Salt
- NSC 681065
- SodiuM 3α,12α-Dihydroxy-5β-cholanate
- Choleic Acid Sodium Salt
Deoxycholic Acid Sodium Salt
Sodium Choleate
- Choleic Acid Sodium Salt
Sodium Choleate
Deoxycholic Acid Sodium Salt
- SodiuM deoxycholate SodiuM Deoxycholic
- Deoxycholic acid, sodiuM salt, extra pure, 99% 100GR
- Deoxycholic acid, sodiuM salt, extra pure, 99% 25GR
- Sodium deoxycholate Vetec(TM) reagent grade, >=97%
- Cholan-24-oic acid, 3,12-dihydroxy-, sodium salt (1:1), (3α,5β,12α)-
- 5b-Cholan-24-oic acid-3a,12a-diole sodium salt
- Sodium deoxycholate≥ 99% (Titration)
- Deoxycholic Acid, Sodium Salt, ULTROL
- N' N-DIMETHYLFORMAMIDE REAGENT GRADE
- SODIUM DEOXYCHOLATE BIOXTRA, >= 98.&
- 7-DEOXYCHOLIC ACID SODIUM SALT
- 5BETA-CHOLANIC ACID-3ALPHA,12ALPHA-DIOL SODIUM
- 5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL SODIUM SALT
- 5-BETA-CHOLAN-24-OIC ACID-3A,12A-DIOLE SODIUM SALT
- 3A,12A-DIHYDROXYCHOLANIC ACID SODIUM SALT
- 3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLANIC ACID SODIUM SALT
- 3ALPHA,12ALPHA-DIHYDROXY-5-BETA-CHOLAN-24-OIC ACID, SODIUM SALT
- (3-alpha,5-beta,12-alpha)-12-dihydroxy-cholan-24-oicacidmonosodiumsalt
- 3,12-dihydroxy-,monosodiumsalt,(3.alpha.,5.beta.,12.alpha.)-Cholan-24-oicacid
- 3-alpha,12-alpha-dihydroxy-5-beta-cholan-24-oicacisodiumsalt
- cholan-24-oicacid,3,12-dihydroxy-,monosodiumsalt,(3-alpha,5-beta,12-alph
- cholan-24-oicacid,3,12-dihydroxy-,monosodiumsalt,(3alpha,5beta,12alpha)
