天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Vecuroniumbromid

Vecuronium bromide Struktur
50700-72-6
CAS-Nr.
50700-72-6
Bezeichnung:
Vecuroniumbromid
Englisch Name:
Vecuronium bromide
Synonyma:
vecuronium;norcuron;Vecuronim Bromide;VBMC;nc-45;orgnc45;Musculax;Muscurate;mide,diacetate;VECRONIUM BROMIDE
CBNumber:
CB3382859
Summenformel:
C34H57BrN2O4
Molgewicht:
637.73138
MOL-Datei:
50700-72-6.mol

Vecuroniumbromid Eigenschaften

Schmelzpunkt:
227-229°C
alpha 
+30.5~+35.0゜(D/20℃)(c=0.5,dil.HCl)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
L?slichkeit
Slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in acetonitrile and in anhydrous ethanol.
Aggregatzustand
Solid
Farbe
White
Merck 
14,9941
BRN 
4837308
Stabilit?t:
Hygroscopic
InChIKey
VEPSYABRBFXYIB-PWXDFCLTSA-M
CAS Datenbank
50700-72-6(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi,Xn
R-S?tze: 36/37/38-22
S-S?tze: 26-37/39
WGK Germany  3
RTECS-Nr. TN4875000
HS Code  2933399090
Toxizit?t LD50 in mice: 0.061 mg/kg i.v. (Buckett)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit

Vecuroniumbromid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Beschreibung

Vecuronium, 1-[(2β,3α,5α,16β,17β,)-3,17-bis(acetyloxy)-2-(1-piperidinyl) androstan-16-yl]-1-methylpiperidinium bromide (15.1.9), differs from panuronium only in the extent of alkylation. Only the piperidine substituent on C16 of the steroid skeleton is transformed into a quaternary salt.

Chemische Eigenschaften

White Solid

Verwenden

An aminosteroid, competitive neuromuscular blocker agent.

Definition

ChEBI: The organic bromide salt of a 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidinino- and 16beta-N-methylpiperidinium su stituents.

Biologische Funktion

Vecuronium bromide (Norcuron) is chemically identical to pancuronium except for a tertiary amine in place of a quaternary nitrogen. However, some of the drug will exist as the bisquaternary compound, depending on body pH. Vecuronium has a moderate onset of action (2.4 minutes) and a duration of effect of about 50 minutes. Like pancuronium, it does not block ganglia or vagal neuroeffector junctions, does not release histamine, and is eliminated by urinary excretion.

Allgemeine Beschreibung

Vecuronium bromide, 1-(3 ,17 -dihydroxy-2 -piperidino-5 -androstan-16 -yl)-1-methylpiperidinium bromide diacetate (Norcuron), is themonoquaternary analog of pancuronium bromide. It belongsto the class of nondepolarizing neuromuscular blockingagents and produces effects similar to those of drugs in thisclass. It is unstable in the presence of acids and undergoesgradual hydrolysis of its ester functions in aqueous solution.Aqueous solutions have a pH of about 4.0.

Mechanism of action

Vecuronium bromide is a bisquaternary nitrogen compound that acts by competitively binding to nicotinic cholinergic receptors. The binding of vecuronium decreases the opportunity for acetylcholine to bind to the nicotinic receptor at the postjunctional membrane of the myoneural junction. As a result, depolarization is prevented, calcium ions are not released and muscle contraction does not occur.

Pharmakologie

Vecuronium bromide is steroidal agent that was developed in an attempt to reduce the cardiovascular effects of pancuronium. I t is similar in structure to the older drug, differing only in the loss of a methyl group from one quaternary ammonium radical. Thus it is a monoquaternary amine. An intubating dose of 0.1mgkg-1 produces profound neuromuscular block within 3min. This dose produces clinical block for about 30min. Vecuronium rarely produces histamine release, nor does it have any direct cardiovascular effects, although it allows the cardiac effects of other anaesthetic agents, such as bradycardia produced by the opioids, to go unchallenged. Vecuronium is excreted through the kidneys (30%), although to a lesser extent than pancuronium, and undergoes hepatic deacetylation; the deacetylated metabolites have neuromuscular blocking properties. Repeated doses should be used with care in patients with renal or hepatic disease because they accumulate.

Clinical Use

Vecuronium Bromide is usedmainly to produce skeletal muscle relaxation during surgeryand to assist in controlled respiration after general anesthesiahas been induced.

Vecuroniumbromid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Vecuroniumbromid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 463)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Beijing Mesochem Technology Co.,Ltd
+8613651027935
rachel@mesochem.com China 191 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8810 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12835 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
+86-18600796368 +86-18600796368
sales@sjar-tech.com China 456 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497
sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845
sales@amoychem.com China 6383 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5906 58

50700-72-6(Vecuroniumbromid)Verwandte Suche:


  • 1-(3-alpha,17-beta-diacetoxy-2-beta-piperidino-5-alpha-androstan-piperidiniu
  • 17beta-diol,16beta-pipecolinio-2beta-piperidino-5alpha-androstan-3alphbro
  • mide,diacetate
  • nc-45
  • orgnc45
  • 1-(3alpha,17beta-Dihydroxy-2beta-piperidino-5alpha-androstan-16beta,5alpha-yl)-1-methylpiperidinium bromide, diacetate
  • Muscurate
  • VercuoniuM BroMide
  • VecuroniuM broMide(Norcuron)
  • 1-[5,14-bis(acetyloxy)-2,15-diMethyl-4-(piperidin-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-13-yl]-1-Methylpiperidin-1-iuM broMide
  • VecuroniuM BroMide Hydrate
  • Piperidinium, 1-[(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-, bromide (1:1)
  • 1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-piperidinium bromide
  • (Vecuroniun bromide)
  • Vecuronium bromide, >=99%
  • (+)-1-(3,17-diacetoxy-2-piperidino-5-androstan-16-yl)-1-methylpiperidinium bromide
  • VECURONIUM BROMIDE, USP STANDARD
  • VECURONIUM BROMIDE, RELATED COMPOUND A3ALPHA, 17BETA-DIACETYL-OXY-2BETA, 16BETA-BISPIPERIDINYL-5ALPHA-ANDROSTAN USP STANDARD
  • VECURONIUM BROMIDE, EP
  • VECUROMIUM BROMIDE
  • VECURUNIUM BROMIDE
  • Musculax
  • Piperidinium, 1-[(2b,3a,5a,16b,17b)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-, bromide (9CI)
  • VECURONIUM BROMIDE
  • VECRONIUM BROMIDE
  • Piperidinium, 1-[(2,3α,5α ,16,17)-3,17-bis(acetyloxy)-2-(1-piperidinyl )androstan-16-yl]-1-methyl-, bromide
  • 1-[(2, β,3α,5α,16β,17β)-3,17-Bis(acetoxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide
  • VBMC
  • 1-(3,17-Diacetoxy-2-piperidino-5-androstan-16-yl)-
  • VENCURONIUM BROMIDE
  • 5alpha-Androstan-3alpha,17beta-diol,-16beta-pipecolinio-2beta-piperidino-,bromide,diacetate
  • Piperidinium, 1-(3-alpha,17-beta-diacetoxy-2-beta-piperidino-5-alpha-androstan-16-beta-yl)- 1-methyl-, bromide
  • Vecuronium bromide CRS
  • 1-((2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3,17-diacetoxy-10,13-dimethyl-2-(piperidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-methylpiperidin-1-ium bromide
  • 1-((2S,3S,5S,10S,13S,16S,17R)-3,17-Diacetoxy-10,13-dimethyl-2-(piperidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-16-yl)-1-methylpiperidin-1-ium bromide
  • 1-[(2beta,3alpha,5alpha,16beta,17beta)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium Bromide
  • Vecuronium bromide USP/EP/BP
  • 50700-72-6 USP/EP/BP
  • Sodium Picosulfate Impurity 1
  • Pancuronium bromide EP Impurity D
  • Vecuronium Bromide (ORG NC 45)
  • Vecuronium bromideQ: What is Vecuronium bromide Q: What is the CAS Number of Vecuronium bromide Q: What is the storage condition of Vecuronium bromide Q: What are the applications of Vecuronium bromide
  • vecuronium bromide (1167)Q: What is vecuronium bromide (1167) Q: What is the CAS Number of vecuronium bromide (1167)
  • TIANFU-CHEM Vecuronium bromide
  • Vecuronium Bromide (1711155)
  • 1-[(2Beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium bromide hydrate
  • [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetoxy-10,13-dimethyl-16-(1-methylpiperidin-1-ium-1-yl)-2-(1-piperidyl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
  • Vecuronim Bromide
  • vecuronium
  • norcuron
  • Pancuronium Bromide Impurity D as Bromide
  • Pancuronium Bromide EP Impurity D as Bromide
  • 1-[(2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl-, bromide
  • Vecuronium bromide in methanol
  • 50700-72-6
  • 5070-72-6
  • C35H57Br2N2O4
  • C36H61NO4
Copyright 2019 ? ChemicalBook. All rights reserved