7400-08-0
基本信息
對香豆酸
對羥基肉桂酸
反式-4-羥基桂皮酸
反式-4-羥基肉桂酸
對羥基苯丙烯酸
4-羥基肉桂酸
對羥基肉桂酸
4-COUMARIC ACID
4-HYDROXYCINNAMIC ACID
AKOS 221-47
AKOS BAR-2479
COUMARIC ACID, TRANS-P-
LABOTEST-BB LT00452637
P-COUMARIC ACID
P-CUMARIC ACID
PHCA
P-HYDROXYCINNAMIC ACID
P-HYDROXYL CINNAMIC ACID
RARECHEM BK HW 0163
TRANS-4-COUMARIC ACID
TRANS-4-HYDROXYCINNAMIC ACID
TRANS-P-COUMARIC ACID
TRANS-P-CUMARIC ACID
(2E)-3-(4-Hydroxyphenyl)-2-propenoic acid
3-(4-Hydroxyphenyl)-2-propenoic acid
3-(4-hydroxyphenyl)-2-propenoicaci
物理化學性質(zhì)
常見問題列表
Human Endogenous Metabolite
|
TXB 2 371 μM (IC 50 ) |
PGE 2 126 μM (IC 50 ) |
p-Hydroxycinnamic acid (p-Coumaric acid), is a ubiquitous plant metabolite with antioxidant and anti-inflammatory properties. p-Hydroxycinnamic acid (500 μM and 1 mM) reduces ADP-induced platelet aggregation (55?2 (SE 4?01) % and 35?6 (SE 2?35) % relative to basal level, respectively). p-Hydroxycinnamic acid is able to modify platelet function, a shear-inducing device that simulates primary haemostasis. p-Hydroxycinnamic acid interferes also with arachidonic acid cascade, reducing thromboxane B 2 production and lipopolysaccharide-induced prostaglandin E 2 generation (IC 50 371 and 126 μM, respectively).