| Identification | Back Directory | [Name]
herbimycin C | [CAS]
91700-92-4 | [Synonyms]
TAN-420D
herbimycin C
Antibiotic TAN-420D
(15R)-17-Demethoxy-15-methoxygeldanamycin
(15R)-17-Demethoxy-15β-methoxygeldanamycin
Geldanamycin, 17-demethoxy-15-methoxy-, (15R)- | [Molecular Formula]
C29H40N2O9 | [MDL Number]
MFCD14635436 | [MOL File]
91700-92-4.mol | [Molecular Weight]
560.64 |
| Hazard Information | Back Directory | [Uses]
Herbimycin C is a minor analog of herbimycin complex. | [Uses]
Herbimycin C is a minor analogue of the herbimycin complex isolated from Streptomyces hygroscopicus. Herbimycin C possesses potent antitumour activity and converts Rous sarcoma virus-infected rat kidney cells into normal cells. Until now limited access has restricted a full investigation of the properties of herbimycin C. Research on related metabolites, herbimycin A and geldanamycin, has stimulated intensive interest in this class as selective antitumour agents and for prolonging the viability of tissue-cultured cells and organs. |
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