| Identification | Back Directory | [Name]
anguinomycin A | [CAS]
111278-01-4 | [Synonyms]
KR-2827B
anguinomycin A
5-DeMethylleptoMycin A, KR 2827A
2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-
19-[(3,6-Dihydro-6-oxo-2H-pyran)-2-yl]-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoic acid | [Molecular Formula]
C31H44O6 | [MOL File]
111278-01-4.mol | [Molecular Weight]
512.68 |
| Chemical Properties | Back Directory | [Boiling point ]
714.9±60.0 °C(Predicted) | [density ]
1.095±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: Unstable; Ethanol: Soluble; Methanol: Soluble | [form ]
Pale yellow film. | [pka]
5.11±0.33(Predicted) |
| Hazard Information | Back Directory | [Uses]
Anguinomycin A, isolated from a Streptomyces sp., displays nanomolar cytotoxicity to murine P388 leukemia cells. In addition, it shows antitumour activity in vivo against murine Lewis lung carcinoma and P388 leukemia. Anguinomycin A is an analogue of leptomycin B, an inhibitor of nuclear export of proteins. | [storage]
Store at -20°C |
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