| Identification | More | [Name]
Lithium chloride | [CAS]
7447-41-8 | [Synonyms]
LITHIUM ION
LITHIUM ION CHROMATOGRAPHY STANDARD
LITHIUM, ION CHROMATOGRAPHY STANDARD SOLUTION
LITHIUM ION STANDARD
LITHIUM NITRATE
Chlorku litu
chlorkulitu
Chlorure de lithium
chloruredelithium
Hydrochloric acid lithium salt
LiCl
Lithium chloride (LiCl)
lithiumchloride(licl)
Lithiumchloride,anhydrous
Lithium chloride solution
Lithium Chloride, MB Grade (1.05673)
Lithium chloride, Molecular Biology Grade
Lithium Ion standard solution Fluka
LITHIUM CHLORIDE ANYD.
LITHIUM CHLORIDE, REAGENTPLUS, 99.99% | [EINECS(EC#)]
231-212-3 | [Molecular Formula]
ClLi | [MDL Number]
MFCD00064606 | [Molecular Weight]
42.39 | [MOL File]
7447-41-8.mol |
| Chemical Properties | Back Directory | [Appearance]
White powder | [Melting point ]
605 °C (lit.) | [Boiling point ]
1383 °C/1 atm (lit.) | [density ]
2.06 | [vapor pressure ]
1.33 hPa (547 °C) | [refractive index ]
n20/D 1.381
| [Fp ]
-4 °F
| [storage temp. ]
2-8°C
| [solubility ]
H2O: soluble
| [form ]
beads
| [pka]
2.256[at 20 ℃] | [color ]
White to gray | [Specific Gravity]
2.068 | [Odor]
Odorless | [PH]
5.5-7.5 (25℃, 50mg/mL in H2O) | [PH Range]
6 | [Stability:]
Stable. Incompatible with strong oxidizing agents, strong acids, bromine trichloride, bromine trifluoride. Very hygroscopic. Protect from moisture. | [Water Solubility ]
832 g/L (20 ºC) | [Sensitive ]
Hygroscopic | [λmax]
λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01 | [Merck ]
14,5528 | [InChIKey]
KWGKDLIKAYFUFQ-UHFFFAOYSA-M | [LogP]
-1 | [CAS DataBase Reference]
7447-41-8(CAS DataBase Reference) | [NIST Chemistry Reference]
Lithium chloride(7447-41-8) | [EPA Substance Registry System]
7447-41-8(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
F,Xn,C,Xi | [Risk Statements ]
R11:Highly Flammable.
R36/38:Irritating to eyes and skin .
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R35:Causes severe burns.
R10:Flammable.
R36/37:Irritating to eyes and respiratory system .
R19:May form explosive peroxides.
R63:Possible risk of harm to the unborn child.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S16:Keep away from sources of ignition-No smoking .
S36:Wear suitable protective clothing .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S33:Take precautionary measures against static discharges .
S29:Do not empty into drains .
S22:Do not breathe dust . | [WGK Germany ]
1 | [RTECS ]
OJ5950000 | [F ]
3-10 | [TSCA ]
Yes | [HS Code ]
28273980 | [Safety Profile]
Human poison by
ingestion. Experimental poison by
intravenous and intracerebral routes.
Moderately toxic by subcutaneous and
intraperitoneal routes. Experimental
teratogenic and reproductive effects. Human
systemic effects by ingestion: somnolence,
tremors, nausea or vomiting. An eye and
severe skin irritant. Human mutation data
reported. Questionable carcinogen with
experimental neoplastigenic data. This
material has been recommended and used as
a substitute for sodwm chloride in "saltfree" diets, but cases have been reported in
which the ingestion of lithium chloride has
produced dminess, ringing in the ears,
visual disturbances, tremors, and mental
confusion. In most cases, the symptoms
disappeared when use was discontinued.
Prolonged absorption may cause disturbed
electrolyte balance, impaired renal function.
Reaction is violent with BrF3. When heated
to decomposition it emits toxic fumes of
Cl-. Used for dehumidification in the air
conditioning industry. Also used to obtain
lithum metal. See also LITHIUM
COMPOUNDS. | [Hazardous Substances Data]
7447-41-8(Hazardous Substances Data) | [Toxicity]
LD50 in mice (mg/kg): 990 i.p.; in rats (mg/kg): 600 i.p., 4.8 i.v. (Wielosz). |
| Hazard Information | Back Directory | [General Description]
Colorless crystals or powder. Low toxicity. | [Reactivity Profile]
These materials have weak oxidizing or reducing powers. Redox reactions can however still occur. For example, CO2, which is often regarded as chemically inert, vigorously oxidizes the strong reducing agent Mg if the two are heated together. The majority of compounds in this class are slightly soluble or insoluble in water. If soluble in water, then the solutions are usually neither strongly acidic nor strongly basic. These compounds are not water-reactive. Some do react with acids: carbonates generate carbon dioxide and heat when treated with acids; fluorides, sulfites and sulfides generate toxic gases (hydrogen fluoride, sulfur dioxide and hydrogen sulfide, respectively) when treated with acids. | [Air & Water Reactions]
Very hygroscopic. Very soluble in water. | [Fire Hazard]
Flash point data for this chemical are not available. LITHIUM CHLORIDE is probably combustible. | [Physical properties]
White cubic crystals; granules or powder; hygroscopic; sharp salt-like taste; refractive index 1.662; density 2.068 g/cm3; melts at 605°C; vaporizes around 1,360°C; readily dissolves in water (64g/100mL at 0°C); also highly soluble in alcohol and pyridine; moderately soluble in acetone (4.1 g/100mL at 25°C). | [Application]
Lithium chloride(7447-41-8) solution can be used:
(1) obtaining dendritic cells in the form of LiClPAM3 DCs;
(2) LiCl buffer preparation for immunoprecipitation;
(3) in the preparation of washing buffers;
(4) in the preparation of washing buffers for radioimmunoprecipitation assays (RIPA);
(5) can be used for selective precipitation of RNA.
| [Definition]
ChEBI: A metal chloride salt with a Li(+) counterion. | [Flammability and Explosibility]
Nonflammable | [Industrial uses]
Lithium chloride solutions are used in large dehumidification systems in the air-conditioning industry. This use depends on the low equilibrium pressure of water vapor above solutions of lithium chloride. After the solutions have absorbed water, they are regenerated by heating.
Lithium chloride is used in a number of salt mixtures. Such salt mixtures have low melting points allowing the material to be used in brazing fluxes and brazing baths. The molten lithium chloride-potassium chloride eutectic mixture can be used as an electrolyte. The mixture is electrolyzed for the production of lithium metal and is used as an electrolyte in voltaic cells.
Lithium chloride is also used in manufacture of mineral waters; in pyrotechnics; soldering aluminum; in refrigerating machines. | [Biochem/physiol Actions]
Lithium chloride(7447-41-8) has the ability to block glycogen synthase kinase (GSK). It may also possess anti-inflammatory effects at low and non-toxic concentrations.
| [Purification Methods]
Crystallise it from water (1mL/g) or MeOH and dry it for several hours at 130o. Other metal ions can be removed by preliminary crystallisation from hot aqueous 0.01M disodium EDTA. It has also been crystallised from conc HCl, fused in an atmosphere of dry HCl gas, cooled under dry N2 and pulverised in a dry-box. Kolthoff and Bruckenstein [J Am Chem Soc 74 2529 1952] precipitated it with ammonium carbonate, washed it with Li2CO3 five times by decantation and finally with suction, then dissolved it in HCl. The LiCl solution is evaporated slowly with continuous stirring in a large evaporating dish, the dry powder being stored (while still hot) in a desiccator over CaCl2. |
| Questions and Answers (Q&A) | Back Directory | [Chemical Properties]
White cubic crystals; granules or powder; hygroscopic; sharp salt-like
taste; refractive index 1.662; density 2.068 g/cm3; melts at 605°C; vaporizes around 1,360°C; readily dissolves in water (64g/100mL at 0°C); also
highly soluble in alcohol and pyridine; moderately soluble in acetone (4.1
g/100mL at 25°C). | [Uses]
Lithium chloride(7447-41-8) is used in the production of lithium metal by electrolysis. It also is used in metallurgy as a eutectic melting composition with potassium chloride (LiCl 41 mol%: KCl 59 mol%). Other applications are in low temperature dry-cell batteries; as a dehumidifier in air conditioning; in welding and soldering flux; as a desiccant; in fireworks; and in mineral waters and soft drinks.
| [Preparation]
Lithium chloride may be prepared by reaction of lithium carbonate or lithium hydroxide with hydrochloric acid followed by crystallization:
Li2CO3+ 2HCl →2LiCl + CO2+ H2O LiOH + HCl →LiCl + H2O
Crystallization above 95°C yields anhydrous salt. Hot solution upon cooling forms crystals of monohydrate, LiCl.H2O.
Lithium chloride can be synthesized from its elements by heating lithium metal with chlorine gas. It also may be obtained from natural brine.
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