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ChemicalBook--->CAS DataBase List--->62883-00-5

62883-00-5

62883-00-5 Structure

62883-00-5 Structure
IdentificationMore
[Name]

Iopamidol
[CAS]

62883-00-5
[Synonyms]

IOPAMIDOL
N,N'-BIS(1,3-DIHYDROXYPROPAN-2-YL)-5-(2-HYDROXYPROPANOYLAMINO)-2,4,6-TRIIODO-BENZENE-1,3-DICARBOXAMIDE
Iopamidol
N,N'-Bis(2-hydroxy-1-(hydroxymethyl)ethyl)-5-((2-hydroxy-1-oxopropyl)amino)-2,4,6-triiodo-1,3-Benzenedicarboxamide
[EINECS(EC#)]

262-093-6
[Molecular Formula]

C17H22I3N3O8
[MDL Number]

MFCD00867931
[Molecular Weight]

777.09
[MOL File]

62883-00-5.mol
Chemical PropertiesBack Directory
[Melting point ]

>283oC (dec.)
[storage temp. ]

-20°C Freezer, Under inert atmosphere
[solubility ]

Water (Slightly)
[form ]

Solid
[pka]

pKa 10.70(H2O,t = 25.0) (Uncertain)
[color ]

White
[CAS DataBase Reference]

62883-00-5(CAS DataBase Reference)
Hazard InformationBack Directory
[Description]

Lopamidol is a benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2S)-2-hydroxypropanamido group at the 5-position. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic. Lopamidol is a Radiographic Contrast Agent, it is a benzenedicarboxamide, an organoiodine compound and a pentol.
[Uses]

Diagnostic aid (radiopaque medium.
[Definition]

ChEBI: Iopamidol is a benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2S)-2-hydroxypropanamido group at the 5-position. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic. It is a benzenedicarboxamide, an organoiodine compound and a pentol.
[Indications]

Iopamidol is indicated for angiography throughout the cardiovascular system in adults, including cerebral and peripheral arteriography, coronary arteriography and ventriculography, selective visceral arteriography and aortography, peripheral venography (phlebography), and in pediatric patients for angiocardiography; or for intravenous use in adult and pediatric for computed tomographic (CT) imaging of the head and body.
[Brand name]

Isovue (Bracco).
[Side effects]

Serious Effects: Decreased urination, severe headache, dizziness, convulsion, irregular heart beat, feeling light-headed, fainting, breathing trouble, fever, chills, nausea and vomiting.
Local: Pain, tenderness, redness or skin changes.
Less Common: Joint or muscle pain, back ache, stiff neck, numbness, warmth, or tingly feeling, ringing in the ears, increased sweating, itchy skin, chills, stuffy nose, sneezing, confusion, slurred speech.
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