| Identification | More | [Name]
L-Alanine | [CAS]
56-41-7 | [Synonyms]
2-AMINOPROPIONIC ACID
ALA
ALANINE
ALANINE, L-
H-ALA-OH
H-L-ALA-OH
L-2-AMINOPROPANOIC ACID
L-2-AMINOPROPIONIC ACID
L-ALA
L-ALANINE DEXTRO-ROTATORY
L-ALPHA-ALANINE
L-ALPHA-AMINOPROPIONIC ACID
RARECHEM AB PP 0952
(S)-2-AMINOPROPIONIC ACID
(S)-(+)-ALANINE
(S)-2-Aminopropanoic acid
(s)-2-aminopropanoicacid
(S)-2-Aminopropansαure
(S)-2-Aminopropionsαure
2-Aminopropanoic acid | [EINECS(EC#)]
200-273-8 | [Molecular Formula]
C3H7NO2 | [MDL Number]
MFCD00064410 | [Molecular Weight]
89.09 | [MOL File]
56-41-7.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
314.5 °C | [alpha ]
14.5 º (c=10,6N HCl,dry sub.) | [Boiling point ]
212.9±23.0 °C(Predicted) | [density ]
1,432 g/cm3 | [FEMA ]
3818 | [refractive index ]
1.4650 (estimate) | [storage temp. ]
Store at RT. | [solubility ]
H2O: 100 mg/mL
| [form ]
powder
| [pka]
2.34(at 25℃) | [color ]
White to almost white | [Odor]
odorless | [PH]
5.5-6.5 (100g/l, H2O, 20℃) | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Odor Type]
odorless | [optical activity]
[α]20/D +14.0±1°, c = 5% in 5 M HCl | [Water Solubility ]
166.5 g/L (25 ºC) | [λmax]
λ: 260 nm Amax: ≤0.03
λ: 280 nm Amax: ≤0.02 | [Detection Methods]
T,NMR,Rotation | [Merck ]
14,204 | [BRN ]
1720248 | [InChIKey]
QNAYBMKLOCPYGJ-REOHCLBHSA-N | [LogP]
-0.68 | [Uses]
Alanine is an amino acid that can act as a skin-conditioning agent. It is usually used in combination with other amino acids. | [CAS DataBase Reference]
56-41-7(CAS DataBase Reference) | [NIST Chemistry Reference]
Alanine(56-41-7) | [EPA Substance Registry System]
56-41-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [RTECS ]
AY2990000
| [F ]
10 | [TSCA ]
Yes | [HazardClass ]
IRRITANT | [HS Code ]
29224995 | [Safety Profile]
Mutation data reported. When heated to decomposition it emits toxic fumes of Nox | [Hazardous Substances Data]
56-41-7(Hazardous Substances Data) |
| Questions And Answer | Back Directory | [Description]
Alanine (also called 2-aminopropanoic acid, α-aminopropanoic acid) is an amino acid that helps the body convert the simple glucose into energy and eliminate excess toxins from the liver. Amino acids are the building blocks of important proteins and are key to building strong and healthy muscles. Alanine belongs to non-essential amino acids, which can be synthesized by the body. However, all amino acids may become essential if the body is unable to produce them. People with low-protein diets or eating disorders, liver disease, diabetes, or genetic conditions that cause Urea Cycle Disorders (UCDs) may need to take alanine supplements to avoid a deficiency. Alanine has been shown to help protect cells from being damaged during intense aerobic activity when the body cannibalizes muscle protein to produce energy. Alanine is used to support prostate health and is important for the regulation of insulin.
L-alanine is the L-enantiomer of alanine. L-alanine is utilized in clinical nutrition as a component for parenteral and enteral nutrition. L-alanine plays a key role in transferring nitrogen from tissue sites to the liver. L-Alanine is widely used as nutrition supplements, as sweetener and flavor enhancer in the food industry, as flavor enhancer and preservative in the beverage industry, as intermediate for medicine manufacturing in pharmaceutical, as nutritional supplement and sour corrective agent in agriculture/animal feed, and as intermediate in manufacturing of various organic chemicals.
| [References]
[1] http://www.ajiaminoscience.com/products/manufactured_products/l-amino_acids/L-Alanine.aspx
[2] http://www.foodchemadditives.com/applications-uses/1500
[3] http://www.vitaminstuff.com/amino-acid-alanine.html
|
| Hazard Information | Back Directory | [Chemical Properties]
A white, odorless powder having a sweet taste | [Chemical Properties]
White crystalline powder | [Occurrence]
Natural constituent of protein in plants and animals; found in apple, beef, carob, pea, soybean, wine and
zucchini | [Definition]
ChEBI: The L-enantiomer of alanine. | [Preparation]
Anthrobacter oxydans HAP-1 hyper produces DL-alanine in a nongrowth-associated manner. | [General Description]
L-Alanine, a non-essential amino acid,?is produced enzymatically from?L-aspartate using aspartate β-decarboxylase.?It is the smallest among all the amino acids.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. | [Biochem/physiol Actions]
L-Alanine is a nonessential amino acid, which is highly concentrated in muscle. It is a key player in the Glucose-Alanine cycle, which enables the removal of pyruvate and glutamate from muscle to the liver. Once in the liver, glucose is regenerated from pyruvate and returned to the muscle while glutamate ultimately participates in the urea cycle to form urea. The Glucose-Alanine cycle aides to conserve ATP in muscle for muscle contraction, while the energy burden of gluconeogenesis is imposed upon the liver. Alanine inhibits pyruvate kinase to regulate gluconeogenesis and glycolysis in order to maintain glucose homeostasis during starvation. Alanine prevents hepatic autophagy. Alanine formation is a result of transamination of glutamate and pyruvate. | [Purification Methods]
Crystallise alanine from H2O or aqueous EtOH, i.e. crystallise it from 25% EtOH in water, or recrystallise it from 62.5% EtOH, wash it with EtOH and dry it to constant weight in vacuo over P2O5. [Gutter & Kegeles J Am Chem Soc 75 3893 1953, Walsh J Biol Chem 264 2394 1989.] 2,2'-Iminodipropionic acid is a likely impurity. [Beilstein 4 IV 2480. 2481.] |
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