Identification | Back Directory | [Name]
2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-[6-[[[[9-[(2R)-5-hydroxy-2,11-diMethyl-5-oxido-9-oxo-3,6,8,10-tetraoxa-5-phosphadodec-1-yl]-9H-purin-6-yl]aMino]Methyl]aMino]-9H-purin-9-yl]-1-Methylethoxy]Methyl]-, 1,9-bis(1-Methylethyl) ester, 5-ox | [CAS]
1093279-77-6 | [Synonyms]
Mixed dimer Mixed-POC DiMer Tenofov Mixed Dimer Tri-POC Tenofovir DiMer Tri-POC Tenofovir Dimer (> Tri-POC Tenofovir Dimer (>90%) Tenofovir Ester WHO Impurity I Tenofovir disoproxil Impurity F Tenofovir disoproxil Impurity S Tenofovir disoproxil impurity 3 Tenofovir Mixed Disoproxil Dimer Tenofovir Disoproxil Impurity I(IP) Tenofovir Disoproxil Fumarate impurity M Tenofovir Disoproxil Fumarate IP Impurity I Tenofovir Disoproxil Impurity I(IP)(a dimer) ((((((R)-1-(6-((((9-((R)-2-((bis(((isopropoxycarbonyl)oxy)methoxy)phosphoryl)methoxy)propyl)-9H-purin-6-yl)amino)methyl)amino)-9H-purin-9-yl)propan-2-yl)oxy)methyl)(hydroxy)phosphoryl)oxy)methyl isopropyl carbonate ((((((2R)-1-(6-((((9-((2R)-2-((hydroxy(((isopropoxycarbonyl)oxy)methoxy)phosphoryl)methoxy)propyl)-9H-purin-6-yl)amino)methyl)amino)-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(oxy))bis(methylene) diisopropyl bis(carbonate) 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-[6-[[[[9-[(2R)-5-hydroxy-2,11-diMethyl-5-oxido-9-oxo-3,6,8,10-tetraoxa-5-phosphadodec-1-yl]-9H-purin-6-yl]aMino]Methyl]aMino]-9H-purin-9-yl]-1-Methylethoxy]Methyl]-, 1,9-bis(1-Methylethyl) ester, 5-o 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-[6-[[[[9-[(2R)-5-hydroxy-2,11-diMethyl-5-oxido-9-oxo-3,6,8,10-tetraoxa-5-phosphadodec-1-yl]-9H-purin-6-yl]aMino]Methyl]aMino]-9H-purin-9-yl]-1-Methylethoxy]Methyl]-, 1,9-bis(1-Methylethyl) ester, 5-ox Tenofovir impurity 7/Tri-POC Tenofovir Dimer/5-[[(1R)-2-[6-[[[[9-[(2R)-5-Hydroxy-2,11-dimethyl-5-oxido-9-oxo-3,6,8,10-tetraoxa-5-phosphadodec-1-yl]-9H-purin-6-yl]amino]methyl]amino]-9H-purin-9-yl]-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedio 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-[6-[[[[9-[(2R)-5-hydroxy-2,11-dimethyl-5-oxido-9-oxo-3,6,8,10-tetraoxa-5-phosphadodec-1-yl]-9H-purin-6-yl]amino]methyl]amino]-9H-purin-9-yl]-1-methylethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide | [Molecular Formula]
C34H52N10O17P2 | [MOL File]
1093279-77-6.mol | [Molecular Weight]
934.78 |
Chemical Properties | Back Directory | [Melting point ]
66-74°C | [Boiling point ]
994.6±75.0 °C(Predicted) | [density ]
1.52±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under Inert Atmosphere | [solubility ]
Methanol (Slightly) | [form ]
Solid | [pka]
1.87±0.10(Predicted) | [color ]
White to Pale Beige | [Stability:]
Very Hygroscopic |
Hazard Information | Back Directory | [Uses]
Tri-POC Tenofovir Dimer is a dimer of Tenofovir Disoproxil (T018505), an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. It is also used in the preparation of phosphocitrate for the treatment of rheumatoid and osteoarthritis in the elderly. | [Uses]
Tri-POC Tenofovir Dimer is a dimer of Tenofovir Disoproxil (T018505), an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. It is also used
in the preparation of phosphocitrate for the treatment of rheumatoid and osteoarthritis in the elderly. |
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