| Identification | More | [Name]
Dideoxyadenosine | [CAS]
4097-22-7 | [Synonyms]
2',3'-DIDEOXYADENOSINE
BETA-D-2',3'-DIDEOXYADENOSINE
DDA
DIDEOXYADENOSINE
2’,3’-dideoxy-adenosin
2',3'-Dideoxy-D-adenosine
9-(2,3-Dideoxy-beta-D-ribofuranosyl)adenine
2',3'-DIDEOXYADENOSINE extapure
[(2S,5R)-5-(6-Aminopurin-9-yl)oxolan-2-yl]methanol
NSC 98700 | [EINECS(EC#)]
223-853-2 | [Molecular Formula]
C10H13N5O2 | [MDL Number]
MFCD00010534 | [Molecular Weight]
235.24 | [MOL File]
4097-22-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
181-184 °C(lit.) | [alpha ]
D25 -25.2° (c = 1.01 in water) | [Boiling point ]
377.64°C (rough estimate) | [density ]
1.2455 (rough estimate) | [refractive index ]
-34 ° (C=1, H2O) | [storage temp. ]
2-8°C
| [solubility ]
DMF: 1 mg/mL; DMSO: 2 mg/mL; Ethanol: Slightly soluble | [form ]
Powder | [pka]
pKa 3.84(H2O t=25.0±0. I=0.01) (Uncertain) | [color ]
White to Off-white | [Water Solubility ]
43.2g/L(25 ºC) | [Merck ]
3101 | [BRN ]
619924 | [InChIKey]
WVXRAFOPTSTNLL-NKWVEPMBSA-N | [CAS DataBase Reference]
4097-22-7(CAS DataBase Reference) | [EPA Substance Registry System]
4097-22-7(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R34:Causes burns.
R36/37:Irritating to eyes and respiratory system . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S27:Take off immediately all contaminated clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [WGK Germany ]
2
| [RTECS ]
AU7358900
| [HS Code ]
29349990 | [Toxicity]
LD50 oral in mouse: 5gm/kg |
| Hazard Information | Back Directory | [General Description]
Off-white powder. | [Reactivity Profile]
2',3'-DIDEOXYADENOSINE(4097-22-7) may be sensitive to prolonged exposure to light. | [Air & Water Reactions]
Water soluble. | [Health Hazard]
SYMPTOMS: Symptoms of exposure to a related compound include cutaneous eruptions, fever, mouth sores, thrombocytopenia, neutropenia, reversible peripheral neuropathy, gastrointestinal distress, headache, nausea and vomiting. | [Fire Hazard]
Flash point data for this chemical are not available; however, 2',3'-DIDEOXYADENOSINE is probably combustible. | [Chemical Properties]
Beige power | [Uses]
2′,3′-Dideoxyadenosine (ddA), a specific adenylyl cyclase inhibitor, is useful in biological process and pathway studies involving adenylyl cyclase activity and cAMP pool modulation. | [Uses]
A potent anti-HIV agent. | [Uses]
A potent labelled anti-HIV agent. | [Uses]
Dideoxy Adenosine (Didanosine EP Impurity G) is a potent anti-HIV agent. | [Definition]
ChEBI: A purine 2',3'-dideoxyribonucleoside in which the nucleobase component is specified as adenine. | [storage]
4°C, protect from light |
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