| Identification | More | [Name]
2',3'-Dideoxythymidine | [CAS]
3416-05-5 | [Synonyms]
2',3'-DIDEOXYTHYMIDINE
3'-DEOXYTHYMIDINE
BETA-D-3'-DEOXYTHYMIDINE
DDT
3’-deoxy-thymidin
3'-Deoxy-D-thymidine
3''-DESOXYTHYMIDINE
3''-DEOXYTHYMIDINE (2'', 3''-DIDEOXYTHYMIDINE)
2μ,3μ-Dideoxythymidine, DDT
1-(2,3-Dideoxy-β-D-ribofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
1-[5β-(Hydroxymethyl)tetrahydrofuran-2β-yl]-5-methyluracil
Dideoxythymidine | [EINECS(EC#)]
2017-001-1 | [Molecular Formula]
C10H14N2O4 | [MDL Number]
MFCD00010570 | [Molecular Weight]
226.23 | [MOL File]
3416-05-5.mol |
| Chemical Properties | Back Directory | [Melting point ]
155-156 °C(lit.) | [alpha ]
20 º (C=0.6 IN H2O) | [density ]
1.332±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
DMF: 25 mg/ml,DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml,DMSO: 20 mg/ml | [form ]
Powder | [pka]
9.55±0.10(Predicted) | [color ]
White to Pale Yellow | [optical activity]
[α]19/D +20.0°, c = 0.6 in H2O | [BRN ]
21884 | [InChIKey]
XKKCQTLDIPIRQD-JGVFFNPUSA-N | [CAS DataBase Reference]
3416-05-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [F ]
10-23 | [HS Code ]
29349990 |
| Hazard Information | Back Directory | [Uses]
Research tool for antiviral and anticancer studies. | [Uses]
3’-Deoxythymidine inhibits the ability of bacteriophage T7 to infect Escherichia coli by inhibiting phage DNA synthesis. Also, it is a precursor of DNA polymerase β inhibitor. | [storage]
-20°C | [Purification Methods]
3'-Deoxyuridine is recrystallised from Me2CO/MeOH and is dried in a vacuum. [Michelson & Todd J Chem Soc 816 1955.] |
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