| Identification | More | [Name]
2-Chloropyrimidine | [CAS]
1722-12-9 | [Synonyms]
2-CHLOROPYRIMIDINE
2CPY X HCL
PYRIMIDINE, 2-CHLORO-
2-chloro-pyrimidin
2-Chloropyrimindine
2-choropyrimidine
2-chloropyrimide
Pyrimidine, 2-chloro-(6CI,7CI,8CI,9CI)
2-Chloropyrimidine, 98+%
2-Chloro
2,5-Diamino-4,6-dichloropyrimidine hydrochloride
3-Chloro-6-isopropylaminopyrimidine
2-Chloro-4-deoxyuracil | [EINECS(EC#)]
217-020-2 | [Molecular Formula]
C4H3ClN2 | [MDL Number]
MFCD00006060 | [Molecular Weight]
114.53 | [MOL File]
1722-12-9.mol |
| Chemical Properties | Back Directory | [Appearance]
yellowish to pale orange crystals or cryst. powder | [Melting point ]
63-66 °C (lit.) | [Boiling point ]
75-76 °C/10 mmHg (lit.) | [density ]
1.2710 (rough estimate) | [refractive index ]
1.5320 (estimate) | [Fp ]
98 °C
| [storage temp. ]
Refrigerator | [solubility ]
Methanol, Water | [form ]
Crystals or Crystalline Powder | [pka]
-1.46±0.13(Predicted) | [color ]
Yellow to pale orange | [Water Solubility ]
Slightly soluble in water. 33.3 mg soluble in 1 mL of alcohol. | [Sensitive ]
Moisture Sensitive | [Detection Methods]
GC,NMR | [BRN ]
107171 | [InChIKey]
UNCQVRBWJWWJBF-UHFFFAOYSA-N | [CAS DataBase Reference]
1722-12-9(CAS DataBase Reference) | [NIST Chemistry Reference]
Pyrimidine, 2-chloro-(1722-12-9) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36:Irritating to the eyes.
R36/38:Irritating to eyes and skin .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36:Wear suitable protective clothing . | [RIDADR ]
2811 | [WGK Germany ]
3
| [F ]
10-23 | [Hazard Note ]
Irritant | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
29335900 |
| Hazard Information | Back Directory | [Chemical Properties]
yellowish to pale orange crystals or cryst. powder | [Uses]
2-Chloropyrimidine is a monochlorinated pyrimidine with plant growth regulating activity. Chloropyrimidine is a useful reagent in the preparation of antivirals and other biologically active compounds. | [General Description]
2-Chloropyrimidine undergoes cobalt-catalyzed cross-coupling reaction with aryl halides. | [Purification Methods]
It has been recrystallised from *C6H6, pet ether or a mixture of both. It sublimes at 50o/18mm and can be distilled in a vacuum. [IR: Short & Thompson J Chem Soc 168 1952, Boarland & McOmie J Chem Soc 1218 1951, Beilstein 23/5 V 343.] |
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