| Identification | More | [Name]
Chlorodiphenylphosphine | [CAS]
1079-66-9 | [Synonyms]
AURORA KA-1322
CHLORODIPHENYLPHOSPHINE
DIPHENYLCHLOROPHOSPHINE
Diphenyl phosphine chloride
DIPHENYLPHOSPHINOUS CHLORIDE
DPPC
P-CHLORODIPHENYLPHOSPHINE
PHOSPHINOUS CHLORIDE, DIPHENYL-
diphenyl-phosphinouschlorid
Phosphine, chlorodiphenyl-
Diphenyl chlorophosphine~Diphenylphosphinous chloride
diphneylphosphinous chloride
Chlorodiphenylphosphine, tech., 95+%
Chlorodiphenylphosphine, tech., 95%
Diphenylchlorophosphine,99%
Diphenylchlorophosphine,min.95%
DIPHENYLPHOSPHINE CHLORIDE OR CHLORODIPHENYLPHOSPHINE OR DIPHENYLPHOSPHINOUS CHLORIDE
PH2PCL
Diphenylphosphinchlorid
Diphenyl phosphine chlorideDiphenyl phosphine chloride | [EINECS(EC#)]
214-093-2 | [Molecular Formula]
C12H10ClP | [MDL Number]
MFCD00000529 | [Molecular Weight]
220.63 | [MOL File]
1079-66-9.mol |
| Chemical Properties | Back Directory | [Appearance]
Colorless to light yellow liqui | [Melting point ]
14-16°C | [Boiling point ]
320 °C(lit.)
| [density ]
1.229 g/mL at 25 °C(lit.)
| [vapor density ]
7.8 (vs air)
| [vapor pressure ]
1.3 hPa (20 °C) | [refractive index ]
n20/D 1.636(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Store at R.T. | [solubility ]
Miscible with alcohol. Slightly miscible with ammonia. | [form ]
Liquid | [color ]
Colorless to yellow | [Specific Gravity]
1.229 | [Water Solubility ]
Reacts violently | [Hydrolytic Sensitivity]
8: reacts rapidly with moisture, water, protic solvents | [Sensitive ]
Air & Moisture Sensitive | [Detection Methods]
GC | [BRN ]
512032 | [InChIKey]
XGRJZXREYAXTGV-UHFFFAOYSA-N | [LogP]
5.330 (est) | [CAS DataBase Reference]
1079-66-9(CAS DataBase Reference) | [NIST Chemistry Reference]
Chlorodiphenylphosphine(1079-66-9) | [EPA Substance Registry System]
1079-66-9(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
C | [Risk Statements ]
R14:Reacts violently with water.
R34:Causes burns.
R29:Contact with water liberates toxic gas.
R36:Irritating to the eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S8:Keep container dry .
S30:Never add water to this product .
S25:Avoid contact with eyes .
S27:Take off immediately all contaminated clothing . | [RIDADR ]
UN 3265 8/PG 2
| [WGK Germany ]
2
| [F ]
1-9-19 | [Autoignition Temperature]
320 °C | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29310095 | [Toxicity]
LD50 orally in Rabbit: 316 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless to light yellow liqui | [Uses]
Chlorodiphenylphosphine is used to introduce the diphenylphosphinyl moiety by aryl ortho-lithiation. It is also used as an intermediate to make antioxidants, flame retardants, stabilizers, catalysts, photoinitiators, and optical brighteners. Used as a halogenation reagent for the conversion of alcohols into halides, in the preparation of solid-phase reagent for the conversion of alcohols to alkyl halides. | [Production Methods]
The specific synthesis steps of Chlorodiphenylphosphine are as follows: In a sealed NMR tube filled with argon,Dissolve Ph2P (O) H (0.05 mmol) in 0.5 mL of tetrahydrofuran,Add acetyl chloride (the amount of acetyl chloride added is 1.2 times the equivalent of Ph2P (O) H),The mixture was reacted at 100 ° C for 12 hours with a yield of 99%.
| [Synthesis Reference(s)]
Journal of the American Chemical Society, 77, p. 3526, 1955 DOI: 10.1021/ja01618a030 | [Flammability and Explosibility]
Nonflammable | [Purification Methods]
This air-sensitive, pale yellow lachrymatory liquid is purified by careful fractional distillation and discarding the lower boiling fraction which contains the main impurity PhPCl2 (b 48-51o/0.7mm), and checking for impurities by NMR. [Weinberg J Org Chem 40 3586 1975, Honer et al. Chem Ber 94 2122 1961, Beilstein 16 IV 969.] |
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