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ChemicalBook CAS DataBase List Tropic acid
529-64-6

Tropic acid synthesis

10synthesis methods
The process for preparing tropic acid which comprises reacting sodium phenylacetate with magnesium and isopropyl chloride, reacting the resulting sodium salt of alpha-carboxybenzylmagnesium chloride with formaldehyde, and hydrolyzing the resulting complex.
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: toluene-4-sulfonic acid
3: sodium hydroxide / methanol

References:

Zhu, Dao-Yong;Zhang, Zhen;Mou, Xue-Qing;Tu, Yong-Qiang;Zhang, Fu-Min;Peng, Jin-Bao;Wang, Shao-Hua;Zhang, Shu-Yu [Advanced Synthesis and Catalysis,2015,vol. 357,# 4,p. 747 - 752]

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