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ChemicalBook CAS DataBase List Sodium 4-phenylbutyrate
1716-12-7

Sodium 4-phenylbutyrate synthesis

4synthesis methods
-

Yield:1716-12-7 96%

Reaction Conditions:

with sodium hydroxide in water

Steps:


0.40 g (2.436 mmol) of 4-phenylbutyric acid are suspended in 30 ml of H2O, and then 0.097 g (2.436 mmol) of sodium hydroxide is added. After the acid has been dissolved, the solution is concentrated by rotary evaporation and twice dewatered azeotropically with toluene. This gives 0.44 g (96.0%) of sodium 4-phenylbutyrate in solid form.

References:

BAYER CROPSCIENCE AG US2012/77677, 2012, A1 Location in patent:Page/Page column 3

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