Rosmarinic acid synthesis
- Product Name:Rosmarinic acid
- CAS Number:20283-92-5
- Molecular formula:C18H16O8
- Molecular Weight:360.31
68307-79-9
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20283-92-5
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Yield:-
Steps:
Multi-step reaction with 6 steps
1: 100 percent / H2 / 5percent Pd/C / ethanol / 3750.3 Torr
2: 1.) K2CO3, EtOH, 2.) KOH / 1.) reflux, 5 h, 2.) 12 h
3: 96 percent / tetrahydrofuran / 48 h / 50 °C
5: 94 percent / DMAP, DCC / CH2Cl2 / 12 h / -20 - 20 °C
6: 92 percent / Pd(PPh3)4, morpholine / tetrahydrofuran / Ambient temperature
References:
Eicher, Theophil;Ott, Markus;Speicher, Andreas [Synthesis,1996,# 6,p. 755 - 762]
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20283-92-5
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143815-53-6
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20283-92-5
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23028-17-3
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20283-92-5
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