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ChemicalBook CAS DataBase List Pyridine,2-chloro-6-(1-methylethoxy)-
89481-98-1

Pyridine,2-chloro-6-(1-methylethoxy)- synthesis

6synthesis methods
-

Yield:89481-98-1 91%

Reaction Conditions:

Stage #1: isopropyl alcoholwith potassium tert-butylate in tetrahydrofuran at 20; for 0.5 h;Inert atmosphere;
Stage #2: 2,6-dichloropyridine in tetrahydrofuran at 65; for 12 h;Inert atmosphere;

References:

Cash, Brandon M.;Prevost, Natacha;Wagner, Florence F.;Comins, Daniel L. [Journal of Organic Chemistry,2014,vol. 79,# 12,p. 5740 - 5745] Location in patent:supporting information

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