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ChemicalBook CAS DataBase List 6-THIOPHEN-3-YL-1H-INDAZOLE
281203-98-3

6-THIOPHEN-3-YL-1H-INDAZOLE synthesis

2synthesis methods
79762-54-2 Synthesis
6-Bromoindazole

79762-54-2
374 suppliers
$3.00/1g

6165-69-1 Synthesis
3-Thiopheneboronic acid

6165-69-1
342 suppliers
$12.72/1gm:

-

Yield:281203-98-3 49%

Reaction Conditions:

with dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2;sodium carbonate in 1,4-dioxane;water at 110; under 12751.3 Torr; for 1 h;Microwave irradiation;Inert atmosphere;Suzuki Coupling;

References:

Turner, Lewis D.;Summers, Abbey J.;Johnson, Laura O.;Knowles, Margaret A.;Fishwick, Colin W. G. [ACS Medicinal Chemistry Letters,2017,vol. 8,# 12,p. 1264 - 1268] Location in patent:supporting information

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