ChemicalBook CAS DataBase List 4'-OCTYLOXYACETOPHENONE

4'-OCTYLOXYACETOPHENONE synthesis

4synthesis methods

Product Name:4'-OCTYLOXYACETOPHENONE
CAS Number:37062-63-8
Molecular formula:C16H24O2
Molecular Weight:248.36

111-83-1 Synthesis

111-83-1
498 suppliers
$12.00/25g

99-93-4 Synthesis

99-93-4
883 suppliers
$5.00/25g

37062-63-8
19 suppliers
$712.00/1G

Yield:37062-63-8 99%

Reaction Conditions:

with potassium carbonate in N,N-dimethyl-formamide at 80; for 24 h;

Steps:

2 Synthesis of Compound 1

Take a clean two bottle, add magnet,1.36 g of p-hydroxyacetophenone (about 10 mmol),9.66 g of bromooctane (about 50 mmol),6.91 g of potassium carbonate and 40 ml of anhydrous N,N-dimethylformamide solution.Under magnetic stirring, react at 80°C for 24 h.After the reaction was completed, water/methylene chloride was extracted several times and the organic phases were combined.After separation by a chromatography column, 2.46 g of light yellow liquid was obtained (approximately 99% yield).

References:

CN107501313,2017,A Location in patent:Paragraph 0049; 0051; 0052