天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 1-Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoq
94695-52-0

1-Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoq synthesis

8synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: tetrahydrofuran / 0.75 h / -78 °C
2: 1.) Ac2O / 1.) 150 deg C, 2 h, 2.) t-BuOH, 10 deg C, 30 min; 45 deg C, overnoght
3: t-BuOK / 2-methyl-propan-2-ol / 18 h / 50 °C
4: HCl / acetic acid / 2 h / 100 °C

References:

Domagala, John M.;Heifetz, Carl L.;Hutt, Marland P.;Mich, Thomas F.;Nichols, Jeffry B.;et al. [Journal of Medicinal Chemistry,1988,vol. 31,# 5,p. 991 - 1001]

1-Cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoq Related Search: