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842124-23-6

3-(3,4-DIFLUOROPHENYL)-1-PROPENE synthesis

1synthesis methods
-

Yield:842124-23-6 75%

Reaction Conditions:

Stage #1: 1-bromo-3,4-difluorobenzenewith magnesium;lithium chloride in tetrahydrofuran at 20; for 2 h;Inert atmosphere;
Stage #2: with iron(III)-acetylacetonate in tetrahydrofuran at 0; for 0.0833333 h;Inert atmosphere;
Stage #3: Allyl acetate in tetrahydrofuran at 0; for 0.75 h;Inert atmosphere;

References:

Mayer, Matthias;Czaplik, Waldemar M.;Von Wangelin, Axel Jacobi [Advanced Synthesis and Catalysis,2010,vol. 352,# 13,p. 2147 - 2152] Location in patent:supporting information; experimental part

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