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ChemicalBook >> CAS DataBase List >> UNC 0631

UNC 0631

UNC 0631 price.
  • $37 - $3282.7
  • Product name: UNC 0631
  • CAS: 1320288-19-4
  • MF: C37H61N7O2
  • MW: 635.93
  • EINECS:604-604-1
  • MDL Number:MFCD22683862
  • Synonyms:UNC 0631, >=98%;N-(1-(cyclohexylmethyl)piperidin-4- yl)-2-(4-isopropyl-1,4-diazepan-1-yl)- 6-methoxy-7-(3-(piperidin-1- yl)propoxy)quinazolin-4-amine;UNC 0631;UNC0631/UNC-0631;N-[1-(CyclohexylMethyl)-4-piperidinyl]-2-[hexahydro-4-(1-Methylethyl)-1H-1,4-diazepin-1-yl]-6-Methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinaMine;N-[1-(Cyclohexylmethyl)-4-piperidinyl]-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinamine UNC0631;N-[1-(Cyclohexylmethyl)-4-piperidinyl]-2-(4-isopropyl-1,4-diazepa n-1-yl)-6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinamine;CS-793
25 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 2x25mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2781AH
  • Product description7-(3-(Piperidin-1-yl)propoxy)-N-(1-(cyclohexylmethyl)piperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxyquinazolin-4-amine
  • Packaging100mg
  • Price$1365
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1127
  • Product descriptionUNC0631
  • Packaging5mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1127
  • Product descriptionUNC0631
  • Packaging10mM(in 1mL DMSO)
  • Price$161
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1127
  • Product descriptionUNC0631
  • Packaging25mg
  • Price$265
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1127
  • Product descriptionUNC0631
  • Packaging100mg
  • Price$695
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1841
  • Product descriptionUNC0631 98%
  • Packaging2x25mg
  • Price$638
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146213
  • Product descriptionUNC0631 >98%
  • Packaging100mg
  • Price$838.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146213
  • Product descriptionUNC0631 >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146213
  • Product descriptionUNC0631 >98%
  • Packaging1g
  • Price$3282.7
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11084
  • Product descriptionUNC0631 ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11084
  • Product descriptionUNC0631 ≥98%
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11084
  • Product descriptionUNC0631 ≥98%
  • Packaging10mg
  • Price$178
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11084
  • Product descriptionUNC0631 ≥98%
  • Packaging25mg
  • Price$353
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM142728
  • Product descriptionN-(1-(cyclohexylmethyl)piperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine 98%
  • Packaging50mg
  • Price$318
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2212
  • Product descriptionUNC0631 99.35%
  • Packaging5mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2212
  • Product descriptionUNC0631 99.35%
  • Packaging10mg
  • Price$240
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2781AH 7-(3-(Piperidin-1-yl)propoxy)-N-(1-(cyclohexylmethyl)piperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxyquinazolin-4-amine 100mg $1365 2021-12-16 Buy
ApexBio Technology B1127 UNC0631 5mg $85 2021-12-16 Buy
ApexBio Technology B1127 UNC0631 10mM(in 1mL DMSO) $161 2021-12-16 Buy
ApexBio Technology B1127 UNC0631 25mg $265 2021-12-16 Buy
ApexBio Technology B1127 UNC0631 100mg $695 2021-12-16 Buy
Axon Medchem Axon1841 UNC0631 98% 2x25mg $638 2021-12-16 Buy
Biorbyt Ltd orb146213 UNC0631 >98% 100mg $838.1 2021-12-16 Buy
Biorbyt Ltd orb146213 UNC0631 >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb146213 UNC0631 >98% 1g $3282.7 2021-12-16 Buy
Cayman Chemical 11084 UNC0631 ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 11084 UNC0631 ≥98% 5mg $116 2024-03-01 Buy
Cayman Chemical 11084 UNC0631 ≥98% 10mg $178 2024-03-01 Buy
Cayman Chemical 11084 UNC0631 ≥98% 25mg $353 2024-03-01 Buy
Chemenu CM142728 N-(1-(cyclohexylmethyl)piperidin-4-yl)-2-(4-isopropyl-1,4-diazepan-1-yl)-6-methoxy-7-(3-(piperidin-1-yl)propoxy)quinazolin-4-amine 98% 50mg $318 2021-12-16 Buy
ChemScene CS-2212 UNC0631 99.35% 5mg $138 2021-12-16 Buy
ChemScene CS-2212 UNC0631 99.35% 10mg $240 2021-12-16 Buy

Properties

Boiling point :763.4±70.0 °C(Predicted)
Density :1.114±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥12.66 mg/mL in EtOH with ultrasonic; ≥18.35 mg/mL in DMSO with gentle warming
form :solid
pka :9.34±0.70(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

UNC0631 is a potent and selective inhibitor of G9a activity in vitro (IC50 = 4 nM) and G9a/GLP-mediated dimethylation of histone 3 on lysine 9 in MDA-MB-231 cells (IC50 = 25 nM). It potently inhibits G9a/GLP activity in a variety of cancer cell lines as well as in the human fetal lung IMR-90 cell line.

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