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ChemicalBook >> CAS DataBase List >> Tizanidine hydrochloride

Tizanidine hydrochloride

Tizanidine hydrochloride price.
  • $27 - $1425
  • Product name: Tizanidine hydrochloride
  • CAS: 64461-82-1
  • MF: C9H9Cl2N5S
  • MW: 290.17
  • EINECS:
  • MDL Number:MFCD00798231
  • Synonyms:1,3-benzothiadiazol-4-amine,5-chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-mono ;5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazolehydrochloride ;SIRDALUD;TERNELIN;TIZANIDINE HCL;TIZANIDINE HYDROCHLORIDE;ZANAFLEX;DS-103-282
41 prices
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Brand
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Arctom
  • Aronis compounds
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Chemtos
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
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  • 100mg
  • 10
  • 10mg
  • 25mg
  • 200mg
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  • 1mL
  • 1g
  • 50
  • 5g
  • 25g
  • y0001700
  • 10mM(in 1mL DMSO)
  • 100g
  • 1ml of 1mg
  • ManufacturerAK Scientific
  • Product numberJ10939
  • Product descriptionTizanidineHCl
  • Packaging25mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67149
  • Product descriptionTizanidine hydrochloride 99%
  • Packaging5g
  • Price$93.9
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67149
  • Product descriptionTizanidine hydrochloride 99%
  • Packaging25g
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1368
  • Product descriptionTizanidineHCl
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1368
  • Product descriptionTizanidineHCl
  • Packaging50mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1368
  • Product descriptionTizanidineHCl
  • Packaging100mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1368
  • Product descriptionTizanidineHCl
  • Packaging500mg
  • Price$553
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS564580
  • Product descriptionTizanidine Hydrochloride 98%
  • Packaging5g
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS564580
  • Product descriptionTizanidine Hydrochloride 98%
  • Packaging25g
  • Price$113
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS564580
  • Product descriptionTizanidine Hydrochloride 98%
  • Packaging100g
  • Price$393
  • Updated2021-12-16
  • Buy
  • ManufacturerAronis compounds
  • Product numberBBC/565
  • Product description5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-aminehydrochloride
  • Packaging1g
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBT164478
  • Product descriptionTizanidine hydrochloride
  • Packaging10mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBT164478
  • Product descriptionTizanidine hydrochloride
  • Packaging100mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16477
  • Product descriptionTizanidine (hydrochloride) ≥98%
  • Packaging10mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16477
  • Product descriptionTizanidine (hydrochloride) ≥98%
  • Packaging25mg
  • Price$142
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16477
  • Product descriptionTizanidine (hydrochloride) ≥98%
  • Packaging50mg
  • Price$254
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J10939 TizanidineHCl 25mg $38 2021-12-16 Buy
Alfa Aesar J67149 Tizanidine hydrochloride 99% 5g $93.9 2023-06-20 Buy
Alfa Aesar J67149 Tizanidine hydrochloride 99% 25g $226 2021-12-16 Buy
ApexBio Technology B1368 TizanidineHCl 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B1368 TizanidineHCl 50mg $77 2021-12-16 Buy
ApexBio Technology B1368 TizanidineHCl 100mg $119 2021-12-16 Buy
ApexBio Technology B1368 TizanidineHCl 500mg $553 2021-12-16 Buy
Arctom AS564580 Tizanidine Hydrochloride 98% 5g $27 2021-12-16 Buy
Arctom AS564580 Tizanidine Hydrochloride 98% 25g $113 2021-12-16 Buy
Arctom AS564580 Tizanidine Hydrochloride 98% 100g $393 2021-12-16 Buy
Aronis compounds BBC/565 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-aminehydrochloride 1g $133 2021-12-16 Buy
Biosynth Carbosynth BT164478 Tizanidine hydrochloride 10mg $54 2021-12-16 Buy
Biosynth Carbosynth BT164478 Tizanidine hydrochloride 100mg $119 2021-12-16 Buy
Cayman Chemical 16477 Tizanidine (hydrochloride) ≥98% 10mg $62 2024-03-01 Buy
Cayman Chemical 16477 Tizanidine (hydrochloride) ≥98% 25mg $142 2024-03-01 Buy
Cayman Chemical 16477 Tizanidine (hydrochloride) ≥98% 50mg $254 2024-03-01 Buy

Properties

Melting point :280 °C
Flash point :9℃
storage temp. :Inert atmosphere,Room Temperature
solubility :H2O: ~29 mg/mL
form :solid
color :white
Merck :14,9485
InChI :InChI=1S/C9H8ClN5S.ClH/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9;/h1-2H,3-4H2,(H2,11,12,13);1H
InChIKey :ZWUKMNZJRDGCTQ-UHFFFAOYSA-N
SMILES :N1=C2C=CC(Cl)=C(NC3NCCN=3)C2=NS1.[H]Cl
CAS DataBase Reference :64461-82-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

As an adrenergic agonist with muscle relaxant activity, tizanidine hydrochloride belongs to the hydrochloride salt form of tizanidine, which is commonly used in the treatment of spasticity, a condition where muscles in human body spasm, cramp, or become tight induced by a variety of medical problems such as multiple sclerosis, spinal cord injury, Lou Gehrig's disease, spastic diplegia, back pain or certain other injuries to the spine or central nervous system. Besides, as a sleep aid and an anticonvulsant, tizanidine hydrochloride has off-label usage for migraine headaches and is effective for some symptoms of fibromyalgia.
As a short-acting muscle relaxer, the antinociceptive effect of tizanidine hydrochloride functions by blocking excess nerve impulses (pain sensations) of the nerve cells that are sent to the brain and control muscle movement, ultimately resulting in muscle relaxation and spasticity alleviation.

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