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ChemicalBook >> CAS DataBase List >> T0070907

T0070907

T0070907 price.
  • $6 - $1593.9
  • Product name: T0070907
  • CAS: 313516-66-4
  • MF: C12H8ClN3O3
  • MW: 277.66
  • EINECS:
  • MDL Number:MFCD00121849
  • Synonyms:2-CHLORO-5-NITRO-N-4-PYRIDINYLBENZAMIDE;2-CHLORO-5-NITRO-N-(4-PYRIDYL)BENZAMIDE;T 0070907;N1-(4-PYRIDYL)-2-CHLORO-5-NITROBENZAMIDE;BenzaMide, 2-chloro-5-nitro-N-4-pyridinyl-;T0070907 - CAS 313516-66-4 - Calbiochem;CS-2314;T0070907 (T-0070907
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Brand
  • Abosyn
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Oakwood
  • Sigma-Aldrich
  • SynQuest Laboratories
  • Tocris
  • TRC
  • Usbiological
Package
  • 25
  • 5mg
  • 1mg
  • 5
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 10mM(in 1mL DMSO)
  • ManufacturerAbosyn
  • Product number61-5075
  • Product description2-chloro-5-nitro-N-(pyridin-4-yl)benzamide 95+%
  • Packaging1g
  • Price$405
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberW5337
  • Product description2-Chloro-5-nitro-N-4-pyridinylbenzamide
  • Packaging100mg
  • Price$151
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberW5337
  • Product description2-Chloro-5-nitro-N-4-pyridinylbenzamide
  • Packaging250mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64455
  • Product description2-Chloro-5-nitro-N-(4-pyridyl)benzamide
  • Packaging10mg
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64455
  • Product description2-Chloro-5-nitro-N-(4-pyridyl)benzamide
  • Packaging50mg
  • Price$444
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA227971
  • Product descriptionT0070907 98+%
  • Packaging5mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA227971
  • Product descriptionT0070907 98+%
  • Packaging10mg
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA227971
  • Product descriptionT0070907 98+%
  • Packaging25mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA227971
  • Product descriptionT0070907 98+%
  • Packaging50mg
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA227971
  • Product descriptionT0070907 98+%
  • Packaging100mg
  • Price$33
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA227971
  • Product descriptionT0070907 98+%
  • Packaging250mg
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA227971
  • Product descriptionT0070907 98+%
  • Packaging1g
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004411
  • Product description2-CHLORO-5-NITRO-N-4-PYRIDINYLBENZAMIDE 95.00%
  • Packaging10MG
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004411
  • Product description2-CHLORO-5-NITRO-N-4-PYRIDINYLBENZAMIDE 95.00%
  • Packaging100MG
  • Price$1593.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4301
  • Product descriptionT0070907
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4301
  • Product descriptionT0070907
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Abosyn 61-5075 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide 95+% 1g $405 2021-12-16 Buy
AK Scientific W5337 2-Chloro-5-nitro-N-4-pyridinylbenzamide 100mg $151 2021-12-16 Buy
AK Scientific W5337 2-Chloro-5-nitro-N-4-pyridinylbenzamide 250mg $198 2021-12-16 Buy
Alfa Aesar J64455 2-Chloro-5-nitro-N-(4-pyridyl)benzamide 10mg $118 2021-12-16 Buy
Alfa Aesar J64455 2-Chloro-5-nitro-N-(4-pyridyl)benzamide 50mg $444 2021-12-16 Buy
Ambeed A227971 T0070907 98+% 5mg $6 2021-12-16 Buy
Ambeed A227971 T0070907 98+% 10mg $9 2021-12-16 Buy
Ambeed A227971 T0070907 98+% 25mg $15 2021-12-16 Buy
Ambeed A227971 T0070907 98+% 50mg $22 2021-12-16 Buy
Ambeed A227971 T0070907 98+% 100mg $33 2021-12-16 Buy
Ambeed A227971 T0070907 98+% 250mg $57 2021-12-16 Buy
Ambeed A227971 T0070907 98+% 1g $155 2021-12-16 Buy
American Custom Chemicals Corporation INB0004411 2-CHLORO-5-NITRO-N-4-PYRIDINYLBENZAMIDE 95.00% 10MG $704.55 2021-12-16 Buy
American Custom Chemicals Corporation INB0004411 2-CHLORO-5-NITRO-N-4-PYRIDINYLBENZAMIDE 95.00% 100MG $1593.9 2021-12-16 Buy
ApexBio Technology A4301 T0070907 10mg $50 2021-12-16 Buy
ApexBio Technology A4301 T0070907 10mM(in 1mL DMSO) $50 2021-12-16 Buy

Properties

Melting point :>184°C (dec.)
Density :1.498
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
form :White solid
color :white
Water Solubility :Soluble in DMSO at 10mg/ml. Insoluble in water.
Sensitive :Light Sensitive

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

The peroxisome proliferator-activated receptor-γ (PPARγ) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones (TZDs). TZDs are a group of structurally related synthetic PPARγ receptor agonists with antidiabetic actions in vivo. There are many PPARγ agonists, including 15-deoxy-Δ12,14-prostaglandin J2 and azelaoyl PAF, which are naturally derived. However, only a few antagonists have been reported. T0070907 is a potent and selective antagonist of the human PPARγ with an apparent IC50 of 1 nM for the binding inhibition of rosiglitazone, a reference TZD. T0070907 covalently binds to Cys313 of PPARγ, inducing conformational changes that block the recruitment of transcriptional cofactors to the PPARγ/RXR heterodimer.

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