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ChemicalBook >> CAS DataBase List >> Rofecoxib

Rofecoxib

Rofecoxib price.
  • $11 - $1500
  • Product name: Rofecoxib
  • CAS: 162011-90-7
  • MF: C17H14O4S
  • MW: 314.36
  • EINECS:803-260-0
  • MDL Number:MFCD00935806
  • Synonyms:4-[4-(MethylSLdfonyl)phenyl]-3-phenyl-2(5H)-furanone;4-[4-(Methylsulfonyl)phenyl]-3-phenyl-;Rofecoxib(Vioxx);Rofecoxib (MK0966);Rofecoxid ;ROFECOXIB;MK-0966;VIOXX
38 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • 25g
  • 10mM(in 1mL DMSO)
  • ManufacturerAHH
  • Product numberMT-58460
  • Product descriptionRofecoxib 98%
  • Packaging1g
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ95479
  • Product descriptionRofecoxib
  • Packaging250mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10420
  • Product descriptionRofecoxib
  • Packaging1g
  • Price$283
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA395001
  • Product descriptionRofecoxib 98%
  • Packaging25mg
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA395001
  • Product descriptionRofecoxib 98%
  • Packaging100mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA395001
  • Product descriptionRofecoxib 98%
  • Packaging250mg
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA395001
  • Product descriptionRofecoxib 98%
  • Packaging1g
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA395001
  • Product descriptionRofecoxib 98%
  • Packaging5g
  • Price$208
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA395001
  • Product descriptionRofecoxib 98%
  • Packaging25g
  • Price$656
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1454
  • Product descriptionRofecoxib
  • Packaging100mg
  • Price$52
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1454
  • Product descriptionRofecoxib
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS544253
  • Product descriptionRofecoxib 98%
  • Packaging25mg
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS544253
  • Product descriptionRofecoxib 98%
  • Packaging100mg
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS544253
  • Product descriptionRofecoxib 98%
  • Packaging250mg
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS544253
  • Product descriptionRofecoxib 98%
  • Packaging1g
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS544253
  • Product descriptionRofecoxib 98%
  • Packaging5g
  • Price$206
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-58460 Rofecoxib 98% 1g $480 2021-12-16 Buy
AK Scientific J95479 Rofecoxib 250mg $73 2021-12-16 Buy
AK Scientific J10420 Rofecoxib 1g $283 2021-12-16 Buy
Ambeed A395001 Rofecoxib 98% 25mg $11 2021-12-16 Buy
Ambeed A395001 Rofecoxib 98% 100mg $15 2021-12-16 Buy
Ambeed A395001 Rofecoxib 98% 250mg $23 2021-12-16 Buy
Ambeed A395001 Rofecoxib 98% 1g $55 2021-12-16 Buy
Ambeed A395001 Rofecoxib 98% 5g $208 2021-12-16 Buy
Ambeed A395001 Rofecoxib 98% 25g $656 2021-12-16 Buy
ApexBio Technology B1454 Rofecoxib 100mg $52 2021-12-16 Buy
ApexBio Technology B1454 Rofecoxib 10mM(in 1mL DMSO) $60 2021-12-16 Buy
Arctom AS544253 Rofecoxib 98% 25mg $11 2021-12-16 Buy
Arctom AS544253 Rofecoxib 98% 100mg $15 2021-12-16 Buy
Arctom AS544253 Rofecoxib 98% 250mg $23 2021-12-16 Buy
Arctom AS544253 Rofecoxib 98% 1g $54 2021-12-16 Buy
Arctom AS544253 Rofecoxib 98% 5g $206 2021-12-16 Buy

Properties

Melting point :207°C
Boiling point :577.6±50.0 °C(Predicted)
Density :1.333±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
color :white to beige
Water Solubility :9mg/L(25 ºC)
Merck :14,8248
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
CAS DataBase Reference :162011-90-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P501 Dispose of contents/container to..…

Description

Rofecoxib ts a non-steroidal anti-inflammatory drug (NSAID) launched in Mexico, its first market, for the management of acute pain and the treatment of osteoarthritis (OA) and primary dysmenorrhea. Rofecoxib can be obtained by several different ways; one example is by arylation of a 4-bromofuranone with a phenylboronic acid under Suzuki conditions. Rofecoxib is a highly selective inhibitor of COX-2, the inducible isoform of cyclooxygenase and therefore exhibits a potent antiinflammatory activity without concomitant gastric or renal toxicities linked to the non-specific COX-1/2 inhibitors. In several clinical studies in patients with knee or hip osteoarthritis, Rofecoxib was evaluated at 12.5-50 mg doses once daily: it demonstrated efficacy for all primary and secondary endpoints at doses considerably weaker than those for classical non-specific NSAIDs, with good tolerance and less adverse effects. Selective COX-2 inhibitors potentially have a large spectrum of activity including new indications such as Alzheimer's disease, colorectal cancer, irritable bowel disease or urinary incontinence.

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