Rebamipide
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- $6 - $1593.9
- Product name: Rebamipide
- CAS: 90098-04-7
- MF: C19H15ClN2O4
- MW: 370.79
- EINECS:1308068-626-2
- MDL Number:MFCD00866895
- Synonyms:(+-)-1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoica ;(+-)-2-(4-chlorobenzoylamino)-3-(2(1h)-quinolinon-4-yl)propionicacid ;Mucosta;Proamipide;2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo- (+-)-4-quinolinepropanoic acid;2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid;2-(4-CHLOROBENZAMIDO)-3-(2-OXO-1,2-DIHYDROQUINOLIN-4-YL)PROPANOIC ACID;OPC-12759, Mucosta, α-[(4-Chlorobenzoyl)-amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic Acid
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Brand
- Activate Scientific
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Arctom
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 5mg
- 10MG
- 25mg
- 100MG
- 500mg
- 1g
- 5G
- 10g
- 25g
- 100g
- ManufacturerActivate Scientific
- Product numberAS112633
- Product descriptionRebamipide 98%
- Packaging1g
- Price$89
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS112633
- Product descriptionRebamipide 98%
- Packaging5G
- Price$307
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1763
- Product descriptionRebamipide 98%
- Packaging100g
- Price$850
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ55007
- Product descriptionRebamipide
- Packaging5g
- Price$176
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberA636
- Product descriptionRebamipide
- Packaging25g
- Price$703
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA141959
- Product description2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacid 98%
- Packaging1g
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA141959
- Product description2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacid 98%
- Packaging5g
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA141959
- Product description2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacid 98%
- Packaging25g
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA141959
- Product description2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacid 98%
- Packaging100g
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008557
- Product descriptionREBAMIPIDE HYDRATE 95.00%
- Packaging1G
- Price$649.43
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004046
- Product descriptionREBAMIPIDE 95.00%
- Packaging10MG
- Price$704.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008557
- Product descriptionREBAMIPIDE HYDRATE 95.00%
- Packaging5G
- Price$925.45
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008557
- Product descriptionREBAMIPIDE HYDRATE 95.00%
- Packaging25G
- Price$1531.34
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0004046
- Product descriptionREBAMIPIDE 95.00%
- Packaging100MG
- Price$1593.9
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS450138
- Product description2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacid 98%
- Packaging1g
- Price$6
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS450138
- Product description2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacid 98%
- Packaging5g
- Price$13
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Activate Scientific | AS112633 | Rebamipide 98% | 1g | $89 | 2021-12-16 | Buy |
| Activate Scientific | AS112633 | Rebamipide 98% | 5G | $307 | 2021-12-16 | Buy |
| AHH | API-1763 | Rebamipide 98% | 100g | $850 | 2021-12-16 | Buy |
| AK Scientific | J55007 | Rebamipide | 5g | $176 | 2021-12-16 | Buy |
| AK Scientific | A636 | Rebamipide | 25g | $703 | 2021-12-16 | Buy |
| Ambeed | A141959 | 2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacid 98% | 1g | $6 | 2021-12-16 | Buy |
| Ambeed | A141959 | 2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacid 98% | 5g | $13 | 2021-12-16 | Buy |
| Ambeed | A141959 | 2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacid 98% | 25g | $45 | 2021-12-16 | Buy |
| Ambeed | A141959 | 2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacid 98% | 100g | $150 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008557 | REBAMIPIDE HYDRATE 95.00% | 1G | $649.43 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004046 | REBAMIPIDE 95.00% | 10MG | $704.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008557 | REBAMIPIDE HYDRATE 95.00% | 5G | $925.45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008557 | REBAMIPIDE HYDRATE 95.00% | 25G | $1531.34 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0004046 | REBAMIPIDE 95.00% | 100MG | $1593.9 | 2021-12-16 | Buy |
| Arctom | AS450138 | 2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacid 98% | 1g | $6 | 2021-12-16 | Buy |
| Arctom | AS450138 | 2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoicacid 98% | 5g | $13 | 2021-12-16 | Buy |
Properties
Melting point :288-290°C dec.
Boiling point :695.0±55.0 °C(Predicted)
Density :1.394±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: >5mg/mL
pka :3.38±0.10(Predicted)
form :powder
color :white
Merck :14,8124
InChIKey :ALLWOAVDORUJLA-UHFFFAOYSA-N
CAS DataBase Reference :90098-04-7(CAS DataBase Reference)
Boiling point :695.0±55.0 °C(Predicted)
Density :1.394±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: >5mg/mL
pka :3.38±0.10(Predicted)
form :powder
color :white
Merck :14,8124
InChIKey :ALLWOAVDORUJLA-UHFFFAOYSA-N
CAS DataBase Reference :90098-04-7(CAS DataBase Reference)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Rebamipide is a quinolinone derivative that stimulates endogenous PGE2 generation in gastric mucosa, enhancing gastric mucosal defense in a COX-2-dependent manner.Rebamipide has been shown to inhibit the production of reactive oxygen species and to decrease cytokine release induced by H. pylori infection.
A daily oral dose of 100 mg/kg was found to be protective against the development of pyloric channel ulcers in Mongolian gerbils infected with H. pylori.
In addition to the stomach, rebamipide can also enhance secretion of mucin covering the conjunctiva and cornea, which is important for tear film adhesion.
Rebamipide, a gastroprotective drug, was developed in Japan and was proven to be superior to cetraxate, the former most prescribed drug of the same category, in 1989 in the treatment for gastric ulcers. The initially discovered basic mechanisms of action of rebamipide included its action as a prostaglandin inducer and oxygen free-radical scavenger. In the last 5 years, several basic and clinical studies have been performed for functional dyspepsia, chronic gastritis, NSAID-induced gastrointestinal injuries, gastric ulcer following eradication therapy for Helicobacter pylori, gastric ulcer after endoscopic surgery and ulcerative colitis. In addition, several molecules have been identified as therapeutic targets of rebamipide to explain its pleiotropic pharmacological actions.
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Suppliers and manufacturers
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Shanghai Time Chemicals CO., Ltd.
Xiamen AmoyChem Co., Ltd
BOC Sciences
