天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> ROR gamma-t-IN-1

ROR gamma-t-IN-1

ROR gamma-t-IN-1 price.
  • $44 - $2976
  • Product name: ROR gamma-t-IN-1
  • CAS: 1426802-50-7
  • MF: C23H18Cl2F3NO4S
  • MW: 532.36
  • EINECS:
  • MDL Number:MFCD28902182
  • Synonyms:ROR gamma-t-IN-1;GSK805;GSK805 (GSK-805);N-(2,6-dichloro-2'-(trifluoromethoxy)biphenyl-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide;4-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methyl-2,7-naphthyridin-1(2H)-one;Benzeneacetamide, N-[2,6-dichloro-2'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]-4-(ethylsulfonyl)-;N-[2,6-Dichloro-2'-(trifluoromethoxy)[1,1'-biphenyl]-4-yl]-4-(ethylsulfonyl)benzeneacetamide;N-[3,5-dichloro-4-[2-(trifluoromethoxy)phenyl]phenyl]-2-(4-ethylsulfonylphenyl)acetamide
21 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • ManufacturerAK Scientific
  • Product number2948DU
  • Product descriptionRORgamma-t-IN-1
  • Packaging10mg
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA769555
  • Product descriptionN-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 98+%
  • Packaging1mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA769555
  • Product descriptionN-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 98+%
  • Packaging5mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA769555
  • Product descriptionN-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 98+%
  • Packaging10mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA769555
  • Product descriptionN-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 98+%
  • Packaging25mg
  • Price$486
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA769555
  • Product descriptionN-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 98+%
  • Packaging50mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA769555
  • Product descriptionN-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 98+%
  • Packaging100mg
  • Price$1755
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number9002444
  • Product descriptionGSK805 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9002444
  • Product descriptionGSK805 ≥98%
  • Packaging5mg
  • Price$151
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number9002444
  • Product descriptionGSK805 ≥98%
  • Packaging10mg
  • Price$235
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5079
  • Product descriptionGSK805 97.14%
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5079
  • Product descriptionGSK805 97.14%
  • Packaging10mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5079
  • Product descriptionGSK805 97.14%
  • Packaging25mg
  • Price$560
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5079
  • Product descriptionGSK805 97.14%
  • Packaging50mg
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5079
  • Product descriptionGSK805 97.14%
  • Packaging100mg
  • Price$1750
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003528
  • Product descriptionRORgamma-t-IN-1 98+%
  • Packaging100mg
  • Price$2976
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2948DU RORgamma-t-IN-1 10mg $360 2021-12-16 Buy
Ambeed A769555 N-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 98+% 1mg $45 2021-12-16 Buy
Ambeed A769555 N-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 98+% 5mg $135 2021-12-16 Buy
Ambeed A769555 N-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 98+% 10mg $225 2021-12-16 Buy
Ambeed A769555 N-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 98+% 25mg $486 2021-12-16 Buy
Ambeed A769555 N-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 98+% 50mg $900 2021-12-16 Buy
Ambeed A769555 N-(2,6-dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide 98+% 100mg $1755 2021-12-16 Buy
Cayman Chemical 9002444 GSK805 ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 9002444 GSK805 ≥98% 5mg $151 2024-03-01 Buy
Cayman Chemical 9002444 GSK805 ≥98% 10mg $235 2024-03-01 Buy
ChemScene CS-5079 GSK805 97.14% 5mg $160 2021-12-16 Buy
ChemScene CS-5079 GSK805 97.14% 10mg $280 2021-12-16 Buy
ChemScene CS-5079 GSK805 97.14% 25mg $560 2021-12-16 Buy
ChemScene CS-5079 GSK805 97.14% 50mg $1100 2021-12-16 Buy
ChemScene CS-5079 GSK805 97.14% 100mg $1750 2021-12-16 Buy
Crysdot CD31003528 RORgamma-t-IN-1 98+% 100mg $2976 2021-12-16 Buy

Properties

Boiling point :617.1±55.0 °C(Predicted)
Density :1.434±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMF:3.0(Max Conc. mg/mL);5.64(Max Conc. mM)
DMSO:68.33(Max Conc. mg/mL);128.36(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.56(Max Conc. mM)
Ethanol:50.0(Max Conc. mg/mL);93.92(Max Conc. mM) form :A crystalline solid
pka :12.33±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

GSK805 is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor''s putative ligand binding domain without exerting significant effects on DNA binding. It inhibits the expression of IL-17 (at 0.5 μM) in naïve CD4+ T cells activated under Th17-cell-polarizing conditions and affects the broader RORγt-dependent gene network, inhibiting the development and pathogenic function of Th17 cells. GSK805 significantly reduces the severity of experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis, when given orally to the hosts at 10 mg/kg daily beginning at the time of disease induction.

Related product price