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ChemicalBook >> CAS DataBase List >> 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol

4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol

4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol price.
  • $28 - $4469.3
  • Product name: 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol
  • CAS: 937174-76-0
  • MF: C21H27N7O3
  • MW: 425.48
  • EINECS:
  • MDL Number:MFCD14105605
  • Synonyms:4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol;(S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridi;(R)-4-(2-(4-AMINO-1,2,5-OXADIAZOL-3-YL)-1-ETHYL-7-(PIPERIDIN-3-YLMETHOXY)-1H-IMI;4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-((S)-piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol;4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol GSK 690693;4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol;GSK690693, >=98%;(S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyr
43 prices
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  • Activate Scientific
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
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  • 1unit
  • 10
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerActivate Scientific
  • Product numberAS10002
  • Product descriptionGSK690693 95+% ee
  • Packaging1mg
  • Price$87
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS10002
  • Product descriptionGSK690693 95+% ee
  • Packaging5mg
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3628-M005
  • Product descriptionGSK690693 ≥95%
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1043
  • Product descriptionGSK-690693
  • Packaging10mg
  • Price$185
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA111141
  • Product description(S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+%
  • Packaging1mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA111141
  • Product description(S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+%
  • Packaging5mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA111141
  • Product description(S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+%
  • Packaging10mg
  • Price$101
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA111141
  • Product description(S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+%
  • Packaging50mg
  • Price$302
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA111141
  • Product description(S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+%
  • Packaging100mg
  • Price$495
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA111141
  • Product description(S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+%
  • Packaging250mg
  • Price$991
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA111141
  • Product description(S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+%
  • Packaging1g
  • Price$2824
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000687
  • Product descriptionGSK-690693 95.00%
  • Packaging1MG
  • Price$191.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000687
  • Product descriptionGSK-690693 95.00%
  • Packaging5MG
  • Price$822.8
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000687
  • Product descriptionGSK-690693 95.00%
  • Packaging25MG
  • Price$1386
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA5072
  • Product descriptionGSK690693
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA5072
  • Product descriptionGSK690693
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS10002 GSK690693 95+% ee 1mg $87 2021-12-16 Buy
Activate Scientific AS10002 GSK690693 95+% ee 5mg $149 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3628-M005 GSK690693 ≥95% 5mg $95 2021-12-16 Buy
AK Scientific SYN1043 GSK-690693 10mg $185 2021-12-16 Buy
Ambeed A111141 (S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+% 1mg $40 2021-12-16 Buy
Ambeed A111141 (S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+% 5mg $67 2021-12-16 Buy
Ambeed A111141 (S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+% 10mg $101 2021-12-16 Buy
Ambeed A111141 (S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+% 50mg $302 2021-12-16 Buy
Ambeed A111141 (S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+% 100mg $495 2021-12-16 Buy
Ambeed A111141 (S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+% 250mg $991 2021-12-16 Buy
Ambeed A111141 (S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol 98+% 1g $2824 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000687 GSK-690693 95.00% 1MG $191.1 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000687 GSK-690693 95.00% 5MG $822.8 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000687 GSK-690693 95.00% 25MG $1386 2021-12-16 Buy
ApexBio Technology A5072 GSK690693 1unit $28 2021-12-16 Buy
ApexBio Technology A5072 GSK690693 5mg $70 2021-12-16 Buy

Properties

Boiling point :683.8±65.0 °C(Predicted)
Density :1.41
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL (clear solution)
pka :13.11±0.29(Predicted)
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

GSK690693 is an ATP-competitive, pan-Akt kinase inhibitor with IC50 values of 2, 13, and 9 nM for Akt1, 2, and 3, respectively. It also inhibits other members of the AGC kinase family, including AMPK, DAPK3, PAKs, PKA, PKC, PKG, and PrkX (IC50 values range from 2-81 nM). By preventing the phosphorylation of downstream Akt substrates, GSK690693 has been shown to inhibit proliferation and to induce apoptosis in various human tumor cells in vitro and in xenografts in immunocompromised mice.

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