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ChemicalBook >> CAS DataBase List >> GSK5959

GSK5959

GSK5959 price.
  • $32 - $666
  • Product name: GSK5959
  • CAS: 901245-65-6
  • MF: C22H26N4O3
  • MW: 394.47
  • EINECS:
  • MDL Number:MFCD14744183
  • Synonyms:GSK5959;Benzamide, N-[2,3-dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxy-;CS-1636;GSK-5959;GSK5959;N-[2,3-Dihydro-1,3-dimethyl-2-oxo-6-(1-piperidinyl)-1H-benzimidazol-5-yl]-2-methoxybenzamide;BRPF1-IN-3;BRPF3,GSK5959,bromodomain,Inhibitor,inhibit,BRD1,BRPF1,Epigenetic Reader Domain,GSK-5959,GSK 5959,BRPF2,epigenetics;N-(1,3-dimethyl-2-oxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-methoxybenzamide
22 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • BroadPharm
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 50
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number1994CW
  • Product descriptionCID15990224
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1994CW
  • Product descriptionCID15990224
  • Packaging5mg
  • Price$209
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1994CW
  • Product descriptionCID15990224
  • Packaging10mg
  • Price$302
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4916
  • Product descriptionGSK5959
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4916
  • Product descriptionGSK5959
  • Packaging50mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerBroadPharm
  • Product numberBP-25353
  • Product descriptionGSK5959
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18123
  • Product descriptionGSK5959 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18123
  • Product descriptionGSK5959 ≥98%
  • Packaging5mg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18123
  • Product descriptionGSK5959 ≥98%
  • Packaging10mg
  • Price$184
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18123
  • Product descriptionGSK5959 ≥98%
  • Packaging25mg
  • Price$381
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4867
  • Product descriptionGSK-5959 98.42%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4867
  • Product descriptionGSK-5959 98.42%
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4867
  • Product descriptionGSK-5959 98.42%
  • Packaging50mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000345
  • Product descriptionGSK-5959 98+%
  • Packaging5mg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000345
  • Product descriptionGSK-5959 98+%
  • Packaging10mg
  • Price$157
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000345
  • Product descriptionGSK-5959 98+%
  • Packaging50mg
  • Price$627
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1994CW CID15990224 1mg $133 2021-12-16 Buy
AK Scientific 1994CW CID15990224 5mg $209 2021-12-16 Buy
AK Scientific 1994CW CID15990224 10mg $302 2021-12-16 Buy
ApexBio Technology B4916 GSK5959 10mg $150 2021-12-16 Buy
ApexBio Technology B4916 GSK5959 50mg $450 2021-12-16 Buy
BroadPharm BP-25353 GSK5959 10mg $140 2021-12-16 Buy
Cayman Chemical 18123 GSK5959 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 18123 GSK5959 ≥98% 5mg $100 2024-03-01 Buy
Cayman Chemical 18123 GSK5959 ≥98% 10mg $184 2024-03-01 Buy
Cayman Chemical 18123 GSK5959 ≥98% 25mg $381 2024-03-01 Buy
ChemScene CS-4867 GSK-5959 98.42% 5mg $60 2021-12-16 Buy
ChemScene CS-4867 GSK-5959 98.42% 10mg $100 2021-12-16 Buy
ChemScene CS-4867 GSK-5959 98.42% 50mg $290 2021-12-16 Buy
Crysdot CD31000345 GSK-5959 98+% 5mg $98 2021-12-16 Buy
Crysdot CD31000345 GSK-5959 98+% 10mg $157 2021-12-16 Buy
Crysdot CD31000345 GSK-5959 98+% 50mg $627 2021-12-16 Buy

Properties

Boiling point :527.3±50.0 °C(Predicted)
Density :1.263±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 13 mg/mL (32.96 mM; Need ultrasonic and warming)
form :Powder
pka :13.06±0.20(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The bromodomain and PHD finger-containing (BRPF) proteins are scaffolding components of chromatin-binding MOZ/MORF histone acetyltransferase complexes, which have activity as transcriptional regulators. BRPF1 (BR140 or Peregrin) is important for maintaining Hox gene expression and the development of multiple tissues, axial skeleton, and the hematopoietic system. GSK5959 is a potent, cell-permeable inhibitor of the BRPF1 bromodomain (IC50 = 80 nM). It exhibits greater than 100-fold selectivity for the BRPF1 bromodomain over a panel of 35 other bromodomains. GSK5959 disrupts chromatin binding of BRPF1 in a cellular assay by blocking the interaction of BRPF1 with histone H3.3.